Document Detail


Serum lactate dehydrogenase in head and neck malignancy patients.
MedLine Citation:
PMID:  8449558     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
50 patients of head and neck malignancy were selected for this study while excluding those associated with renal, hepatic, cardiac and metabolic diseases. Age and sex matched even number of controls were also included for comparison. Serum LDH levels in the control group were 124.2 +/- 3.50 I.U./L. Higher levels of LDH were observed in patients with malignancy of head and neck (335.50 +/- 21.60 I.U./L, P < 0.001). Serum LDH level was also related to histopathological stage of malignancy, being higher in poorly differentiated tumour as compared to moderate and well differentiated malignancy. Patients without metastasis had insignificantly lower serum LDH levels as compared to those with metastasis.
Authors:
S K Singh; S A Hasan; S C Sharma; K Chandra; R Ali
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Indian journal of physiology and pharmacology     Volume:  37     ISSN:  0019-5499     ISO Abbreviation:  Indian J. Physiol. Pharmacol.     Publication Date:  1993 Jan 
Date Detail:
Created Date:  1993-04-12     Completed Date:  1993-04-12     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0374707     Medline TA:  Indian J Physiol Pharmacol     Country:  INDIA    
Other Details:
Languages:  eng     Pagination:  93-4     Citation Subset:  IM    
Affiliation:
Department of Otorhinolaryngology, J.N. Medical College, Aligarh Muslim University.
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MeSH Terms
Descriptor/Qualifier:
Adult
Aged
Female
Head and Neck Neoplasms / enzymology*
Humans
L-Lactate Dehydrogenase / blood*
Male
Middle Aged
Prognosis
Tumor Markers, Biological / blood*
Chemical
Reg. No./Substance:
0/Tumor Markers, Biological; EC 1.1.1.27/L-Lactate Dehydrogenase

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