Document Detail

Serum interleukin-1 beta is increased in cluster headache.
MedLine Citation:
PMID:  7694804     Owner:  NLM     Status:  MEDLINE    
We measured serum interleukin-1 beta (IL-1 beta) in 24 episodic cluster headache (CH) patients and 45 normal controls using a specific ELISA method. There was an increase in IL-1 beta in all CH patients compared to controls. IL-1 beta was further increased during the ictal phase of CH compared to patients between attacks and normal individuals. Between attacks, IL-1 beta was also significantly increased compared to controls. We suggest that these results represent an activation of the immune system in CH.
P Martelletti; M Granata; M Giacovazzo
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Publication Detail:
Type:  Comparative Study; Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Cephalalgia : an international journal of headache     Volume:  13     ISSN:  0333-1024     ISO Abbreviation:  Cephalalgia     Publication Date:  1993 Oct 
Date Detail:
Created Date:  1993-12-30     Completed Date:  1993-12-30     Revised Date:  2008-02-11    
Medline Journal Info:
Nlm Unique ID:  8200710     Medline TA:  Cephalalgia     Country:  NORWAY    
Other Details:
Languages:  eng     Pagination:  343-5; discussion 307-8     Citation Subset:  IM    
Headache Centre, University La Sapienza, Rome, Italy.
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MeSH Terms
Cluster Headache / blood*,  immunology,  metabolism
Interleukin-1 / blood*,  immunology
Middle Aged
Substance P / metabolism
Reg. No./Substance:
0/Interleukin-1; 33507-63-0/Substance P

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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