Document Detail

Serum immunoglobulins in patients with iron deficiency anemia.
MedLine Citation:
PMID:  21629635     Owner:  NLM     Status:  PubMed-not-MEDLINE    
Iron deficiency is a common cause of anemia worldwide. Documentation shows that these patients have impaired immunity and are prone to infections. The aim of this study was to confirm whether serum immunoglobulins change in adult nonpregnant females with iron deficiency anemia. Based on patients' clinical history, CBC results, and serum ferritin, iron and total iron binding capacity, 45 healthy patients and 45 iron deficiency anemia (hypochrom microcytic) patients were entered into this case-control study. Serum IgG, IgA and IgM were measured in patient and control groups using the nephelometry method. Both of the groups were compared using suitable statistical test. Mean serum values of IgG, IgA and IgM in the patient group were 12.47 ± 7.67, 1.93 ± 0.92 and 1.35 ± 0.90 g/l respectively. Mean serum values for the control group were 12.51 ± 6.85, 2.14 ± 0.88 and 1.49 ± 0.73 g/l respectively. Although serum immunoglobulins were slightly lower in the patient group compared to the control group these differences were not significant with the t test. Our study showed serum immunoglobulin levels did not change in iron deficiency anemia.
Mohammad Hadi Sadeghian; Mohammad Reza Keramati; Hossein Ayatollahi; Lida Manavifar; Hoda Enaiati; Masoumeh Mahmoudi
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Publication Detail:
Type:  Journal Article     Date:  2010-09-30
Journal Detail:
Title:  Indian journal of hematology & blood transfusion : an official journal of Indian Society of Hematology and Blood Transfusion     Volume:  26     ISSN:  0974-0449     ISO Abbreviation:  Indian J Hematol Blood Transfus     Publication Date:  2010 Jun 
Date Detail:
Created Date:  2011-06-01     Completed Date:  2011-07-14     Revised Date:  2013-05-29    
Medline Journal Info:
Nlm Unique ID:  9425818     Medline TA:  Indian J Hematol Blood Transfus     Country:  India    
Other Details:
Languages:  eng     Pagination:  45-8     Citation Subset:  -    
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