| Serum immunoglobulin E in idiopathic nephrotic syndrome. | |
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MedLine Citation:
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PMID: 15233190 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Serum immunoglobulin E (IgE) and absolute eosinophil count (AEC) were assayed in 48 children with idiopathic nephrotic syndrome and 20 controls. The mean serum IgE (p < 0.001) and AEC (p < 0.05) were significantly raised in active nephrotic syndrome compared with controls. The mean values of IgE and AEC in nephrotic patients were 228.6 and 164.5 per cent of the normal mean, respectively. The serum IgE and AEC were significantly abnormal in all the subgroups (first attack, infrequent, and frequent relapsers), except AEC in infrequent relapses, when compared with the controls. No significant differences in the parameters were observed among the different subgroups of cases. In remission, the mean IgE and AEC were unchanged in comparison with their corresponding values at diagnosis. Thus, the levels are raised not only in active but also in remission, reflecting abnormal immune status even in the disease-free state. |
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Authors:
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O P Mishra; N Ibrahim; Usha; B K Das |
Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Journal of tropical pediatrics Volume: 50 ISSN: 0142-6338 ISO Abbreviation: J. Trop. Pediatr. Publication Date: 2004 Jun |
Date Detail:
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Created Date: 2004-07-05 Completed Date: 2004-07-23 Revised Date: 2006-03-28 |
Medline Journal Info:
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Nlm Unique ID: 8010948 Medline TA: J Trop Pediatr Country: England |
Other Details:
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Languages: eng Pagination: 149-52 Citation Subset: IM |
Affiliation:
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Department of Pediatrics, Institute of Medical Sciences, Banaras Hindu University, India. opmpedia@yahoo.co.uk |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Case-Control Studies Child Child, Preschool Eosinophils / metabolism Humans Immunoglobulin E / blood* India / epidemiology Leukocyte Count Logistic Models Nephrotic Syndrome / epidemiology, immunology* Recurrence |
| Chemical | |
Reg. No./Substance:
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37341-29-0/Immunoglobulin E |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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