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Serum free light chain analysis in multiple myeloma and plasma cell dyscrasias.
MedLine Citation:
PMID:  21162651     Owner:  NLM     Status:  In-Process    
Abstract/OtherAbstract:
After the development of a reliable method to detect free light chains in serum, several investigations have been conducted to explore their importance in plasma cell dyscrasias (PCD). Detection of monoclonal proteins is very important in the diagnosis and management of PCD, which include a broad spectrum of diseases such as multiple myeloma and also benign, premalignant disorders like monoclonal gammopathy of undetermined significance. The aim of this article is to summarize the recent studies and to highlight the importance of free light chain analysis in the diagnosis of PCD, its prognostic value and role in the management of this group of diseases.
Authors:
Guner Hayri Ozsan; Angela Dispenzieri
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Expert review of clinical immunology     Volume:  7     ISSN:  1744-8409     ISO Abbreviation:  Expert Rev Clin Immunol     Publication Date:  2011 Jan 
Date Detail:
Created Date:  2010-12-17     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101271248     Medline TA:  Expert Rev Clin Immunol     Country:  England    
Other Details:
Languages:  eng     Pagination:  65-73     Citation Subset:  IM    
Affiliation:
Division of Hematology, Dokuz Eylul University School of Medicine, Inciralti 35340, Izmir, Turkey.
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