Document Detail


Serum ferritin levels in anemia of rheumatoid arthritis.
MedLine Citation:
PMID:  604478     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Thirty-five anemic patients with rheumatoid arthritis were studied to determine the relationship between serum ferritin levels and body iron status, as assessed by the grading of bone marrow iron stores. The incidence of greatly reduced or absent marrow iron stores was 60%. Peripheral blood smear, RBC indices, serum iron, and iron binding capacity correlated poorly with stainable marrow iron. Serum ferritin levels only correlated approximately with iron stores, and in iron deficient rheumatoid patients the levels were higher than would be expected in patients with uncomplicated iron deficiency. The study shows that reduced marrow iron stores is common in patients with rheumatoid arthritis, and that the serum ferritin concentration may provide a useful indication of reduced body iron stores in these subjects, but only if a range of normal values can be established for this disease.
Authors:
R J Smith; P Davis; A B Thomson; L D Wadsworth; P Fackre
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The Journal of rheumatology     Volume:  4     ISSN:  0315-162X     ISO Abbreviation:  J. Rheumatol.     Publication Date:  1977  
Date Detail:
Created Date:  1978-04-17     Completed Date:  1978-04-17     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  7501984     Medline TA:  J Rheumatol     Country:  CANADA    
Other Details:
Languages:  eng     Pagination:  389-92     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Adult
Aged
Anemia / blood*,  etiology
Arthritis, Rheumatoid / blood,  complications*
Bone Marrow / analysis
Female
Ferritins / blood*
Humans
Iron / analysis
Male
Middle Aged
Chemical
Reg. No./Substance:
7439-89-6/Iron; 9007-73-2/Ferritins

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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