Document Detail


Serum ferritin as indicator of iron responsive anaemia in patients with rheumatoid arthritis.
MedLine Citation:
PMID:  3740984     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
In order to test the hypothesis that serum ferritin below 60 micrograms/l is a good indicator of iron deficiency in patients with rheumatoid arthritis peroral iron was given to 67 patients with active rheumatoid arthritis over a three month period. A rise in haemoglobin concentration was taken as evidence of iron responsive anaemia. In anaemic patients serum ferritin below 60 micrograms/l was a good indicator of iron responsive anaemia, with a predictive value of 83%. Although high plasma transferrin and low mean cell volume showed similar predictive values, more patients with iron deficiency anaemia could be diagnosed by serum ferritin measurements than by other conventional blood tests. In contrast, the predictive value of serum ferritin above 60 micrograms/l was low (50%). The test was of no predictive value in non-anaemic patients. In patients with anaemia and active rheumatoid arthritis serum ferritin is the best blood test currently available for the prediction of iron responsive anaemia.
Authors:
T M Hansen; N E Hansen
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Annals of the rheumatic diseases     Volume:  45     ISSN:  0003-4967     ISO Abbreviation:  Ann. Rheum. Dis.     Publication Date:  1986 Jul 
Date Detail:
Created Date:  1986-09-17     Completed Date:  1986-09-17     Revised Date:  2009-11-18    
Medline Journal Info:
Nlm Unique ID:  0372355     Medline TA:  Ann Rheum Dis     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  596-602     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Adult
Aged
Anemia, Hypochromic / blood*,  complications
Arthritis, Rheumatoid / blood*,  complications
Blood Sedimentation
C-Reactive Protein / analysis
Erythrocyte Indices
Female
Ferritins / blood*
Hemoglobins / analysis
Humans
Iron / blood
Male
Middle Aged
Transferrin / blood
Chemical
Reg. No./Substance:
0/Hemoglobins; 11096-37-0/Transferrin; 7439-89-6/Iron; 9007-41-4/C-Reactive Protein; 9007-73-2/Ferritins
Comments/Corrections

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