Document Detail

Serum erythropoietin concentrations fail to increase after significant phlebotomy losses in ill preterm infants.
MedLine Citation:
PMID:  9447534     Owner:  NLM     Status:  MEDLINE    
RESULTS: Before the first transfusion, erythropoietin concentrations were 68.9 +/- 36.2 mU/ml (range 0 to 205 mU/ml) at 5 ml/kg blood out, 17.4 +/- 8.9 mU/ml at 10 ml/kg, and 4.8 +/- 2.6 mU/ml at 15 ml/kg. Erythropoietin concentrations did not increase in any patients despite increasing phlebotomy losses.
CONCLUSION: Serum erythropoietin concentrations in ill preterm infants do not increase in the face of significant blood loss. Although the mechanistic explanation for this failure is unclear, it likely contributes to the transfusion requirements of this population.
R K Ohls; J Harcum; Y Li; G Davila; R D Christensen
Related Documents :
11747924 - Airway function in infants newly diagnosed with cystic fibrosis.
21133644 - Sudden unexpected death in infancy in denmark.
8917234 - Changing patterns of red blood cell transfusion in very low birth weight infants.
7432874 - Role of exchange transfusion in the treatment of severe septicemia.
22900874 - Snorkelling-related deaths in australia, 1994-2006.
18711734 - Rhesus macaque milk: magnitude, sources, and consequences of individual variation over ...
Publication Detail:
Type:  Comparative Study; Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  Journal of perinatology : official journal of the California Perinatal Association     Volume:  17     ISSN:  0743-8346     ISO Abbreviation:  J Perinatol     Publication Date:    1997 Nov-Dec
Date Detail:
Created Date:  1998-03-04     Completed Date:  1998-03-04     Revised Date:  2013-05-20    
Medline Journal Info:
Nlm Unique ID:  8501884     Medline TA:  J Perinatol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  465-7     Citation Subset:  IM    
Division of Neonatology, University of Florida College of Medicine, Gainesville, USA.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Anemia, Neonatal / blood*,  etiology
Enzyme-Linked Immunosorbent Assay
Erythropoiesis / physiology
Erythropoietin / blood*,  therapeutic use
Infant, Newborn
Infant, Premature, Diseases / blood*,  therapy
Infusions, Intravenous
Phlebotomy / adverse effects*
Recombinant Proteins
Respiration, Artificial
Treatment Outcome
Grant Support
Reg. No./Substance:
0/Recombinant Proteins; 11096-26-7/Erythropoietin

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Endotracheal tolazoline administration in neonates with persistent pulmonary hypertension.
Next Document:  Twins, asymmetric growth restriction, and perinatal morbidity.