Document Detail

Serum enzyme activities in individuals with different levels of physical fitness.
MedLine Citation:
PMID:  8107477     Owner:  NLM     Status:  MEDLINE    
Serum creatine phosphokinase (CPK), aspartate aminotransferase (AST), and alanine aminotransferase (ALT) activities were assayed in 15 healthy but untrained subjects (US) and seven Olympic rowers (OR). Blood samples were obtained at rest, and five and 60 minutes after an ergometer test, during which cardiorespiratory data were obtained. OR demonstrated higher resting CPK (p < 0.001) and AST (p < 0.05) levels than the US. CPK and AST reached their highest levels five minutes after the end of the ergometer test in both groups, whilst peak ALT was reached five and 60 minutes post-test in the US and OR respectively. Fitness parameters and serum enzyme levels were better correlated in the OR group. It is concluded that: (1) exercise temporarily increases the activities of serum AST, ALT, and CPK, (2) increased physical fitness has no bearing on resting serum ALT enzyme levels, although this was not the case with AST and CPK, and (3) exercise duration rather than fitness levels seems to be related to serum CPK, AST, and ALT activities.
Y Koutedakis; A Raafat; N C Sharp; M N Rosmarin; M J Beard; S W Robbins
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The Journal of sports medicine and physical fitness     Volume:  33     ISSN:  0022-4707     ISO Abbreviation:  J Sports Med Phys Fitness     Publication Date:  1993 Sep 
Date Detail:
Created Date:  1994-03-24     Completed Date:  1994-03-24     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0376337     Medline TA:  J Sports Med Phys Fitness     Country:  ITALY    
Other Details:
Languages:  eng     Pagination:  252-7     Citation Subset:  IM    
British Olympic Medical Centre, Northwick Park Hospital, Harrow, Middlesex, England.
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MeSH Terms
Alanine Transaminase / blood*
Anaerobic Threshold / physiology
Aspartate Aminotransferases / blood*
Carbon Dioxide / metabolism
Creatine Kinase / blood*
Exercise Test
Heart Rate / physiology
Oxygen Consumption / physiology
Physical Endurance / physiology
Physical Fitness / physiology*
Respiration / physiology
Sports / physiology*
Time Factors
Reg. No./Substance:
124-38-9/Carbon Dioxide; EC Aminotransferases; EC Transaminase; EC Kinase

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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