Document Detail


Serum creatine kinase in the diagnosis of acute myocardial infarction. Optimal sampling frequency.
MedLine Citation:
PMID:  6401336     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
To document optimal sampling frequency, we reviewed creatine kinase (CK) myocardial specific isoenzyme (CKMB) results in 314 patients with suspected acute myocardial infarction (MI). In 127 patients with elevated CK/CKMB, peak CK observed using all samples (every four-hour [Q4hr] method) was compared with results that would have been obtained had samples been taken on admission and either twice daily (every 12-hour [Q12hr] method) or once daily (every 24-hour [Q24hr] method). Although average peak CK was statistically different (Q4hr greater than Q12hr greater than Q24hr), major underestimation of peak CK (greater than or equal to 500 units/L) was uncommon (3%) using the Q12hr method, suggesting that Q12hr sampling is a practical, cost-effective approach for patients with suspected acute MI.
Authors:
M L Fisher; N H Carliner; L C Becker; R W Peters; G D Plotnick
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Publication Detail:
Type:  Journal Article; Research Support, U.S. Gov't, Non-P.H.S.    
Journal Detail:
Title:  JAMA     Volume:  249     ISSN:  0098-7484     ISO Abbreviation:  JAMA     Publication Date:  1983 Jan 
Date Detail:
Created Date:  1983-02-25     Completed Date:  1983-02-25     Revised Date:  2014-09-17    
Medline Journal Info:
Nlm Unique ID:  7501160     Medline TA:  JAMA     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  393-4     Citation Subset:  AIM; IM    
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MeSH Terms
Descriptor/Qualifier:
Clinical Enzyme Tests*
Cost-Benefit Analysis
Creatine Kinase / blood*
Humans
Isoenzymes
Myocardial Infarction / diagnosis*
Time Factors
Chemical
Reg. No./Substance:
0/Isoenzymes; EC 2.7.3.2/Creatine Kinase

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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