Document Detail

Serum cortisol levels in pregnancy induced hypertension patients.
MedLine Citation:
PMID:  3738913     Owner:  NLM     Status:  MEDLINE    
We measured the serum cortisol levels in 15 normal and 8 pregnancy induced hypertension (PIH) primigravidas. The normal pregnancy had a significant (p less than 0.05) higher cortisol level than that of PIH patient. Especially, 4 severe PIH patients had a significantly (p less than 0.05) lower cortisol level. The lower maternal cortisol level of PIH patients became more significant with the severity of clinical symptoms of PIH. After the onset of labor, the cortisol levels of PIH patients did not elevate compared with normal pregnancy. These data suggest that in the PIH patient the reactivity of the adrenal cortex to adrenocorticotropic hormone (ACTH) may be blunted or the cortisol production in the adrenal cortex may be decreased by the tissue circulation insufficiency due to PIH.
N Furuhashi; H Kono; M Hiruta; T Takahashi; M Tanaka; T Fukaya; O Shinkawa; A Yajima
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The Tohoku journal of experimental medicine     Volume:  149     ISSN:  0040-8727     ISO Abbreviation:  Tohoku J. Exp. Med.     Publication Date:  1986 May 
Date Detail:
Created Date:  1986-09-17     Completed Date:  1986-09-17     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0417355     Medline TA:  Tohoku J Exp Med     Country:  JAPAN    
Other Details:
Languages:  eng     Pagination:  21-4     Citation Subset:  IM    
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MeSH Terms
Hydrocortisone / blood*
Hypertension / blood*
Labor, Obstetric
Pregnancy Complications, Cardiovascular / blood*
Reg. No./Substance:

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