| Serum concentrations of the derivatives of reactive oxygen metabolites (d-ROMs) in dogs with leishmaniosis. | |
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MedLine Citation:
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PMID: 19758830 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Leishmania infantum interferes with the oxidative metabolism of phagocytes. In order to assess whether derivatives of reactive oxygen metabolites (d-ROMs) decrease due to infection or increase due to inflammation, d-ROMs were measured in serum collected from control dogs (Group 1; n = 12), from dogs seropositive for Leishmania either symptomatic (Group 2; n = 27) or not (Group 3; n = 14), and from dogs with other diseases (Group 4; n = 16). The concentrations of d-ROMs in the four groups, expressed in Carratelli Units (U CARR) were, respectively, 75.4 ± 39.5 (median, 81.6), 108.2 ± 96.3 (73.4), 73.5 ± 62.2 (62.0), 127.7 ± 97.3 (94.3). There were no significant differences between groups, but dogs with values higher than the reference interval were found, mostly in Groups 2 and 4 (which had serum C-reactive protein levels consistent with inflammation), whilst low values were occasionally found in Groups 2 and 3. Inflammation may mask decreases in d-ROMs induced by Leishmania infection. |
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Authors:
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Saverio Paltrinieri; Sara Ravicini; Gabriele Rossi; Xavier Roura |
Publication Detail:
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Type: Journal Article Date: 2009-09-15 |
Journal Detail:
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Title: Veterinary journal (London, England : 1997) Volume: 186 ISSN: 1532-2971 ISO Abbreviation: Vet. J. Publication Date: 2010 Dec |
Date Detail:
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Created Date: 2010-12-06 Completed Date: 2011-01-06 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9706281 Medline TA: Vet J Country: England |
Other Details:
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Languages: eng Pagination: 393-5 Citation Subset: IM |
Copyright Information:
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Copyright © 2009 Elsevier Ltd. All rights reserved. |
Affiliation:
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Department of Veterinary Pathology, Hygiene and Public Health, University of Milan, Italy. saverio.paltrinieri@unimi.it |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Animals Case-Control Studies Dog Diseases / blood* Dogs Female Leishmania infantum* Leishmaniasis, Visceral / blood, veterinary* Male Reactive Oxygen Species / blood* |
| Chemical | |
Reg. No./Substance:
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0/Reactive Oxygen Species |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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