| Serum complement factors in human acute pancreatitis. | |
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MedLine Citation:
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PMID: 7345008 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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C3, C4 and total haemolytic activity of serum complement were measured in 35 patients with acute pancreatitis, and were found to be normal or raised in 24 patients (23 survivors). In 3 further patients complement values were low initially, but returned to normal with clinical recovery. In the remaining 8 patients serum complement factors were generally lowered or declined during the course of the disease; all of them died from haemorrhagic pancreatitis. Thus lowered complement factors may be an unfavourable prognostic sign for the course of the disease. Reasons for the decline may be protein loss, blood coagulation disturbances or intrapancreatic activation of complement. The latter possibility is supported by the immunohistological detection of C3 deposits surrounding parenchymal necroses in two patients. |
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Authors:
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P G Lankisch; H Koop; U Kaboth |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Hepato-gastroenterology Volume: 28 ISSN: 0172-6390 ISO Abbreviation: Hepatogastroenterology Publication Date: 1981 Oct |
Date Detail:
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Created Date: 1982-09-10 Completed Date: 1982-09-10 Revised Date: 2005-11-17 |
Medline Journal Info:
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Nlm Unique ID: 8007849 Medline TA: Hepatogastroenterology Country: GERMANY, WEST |
Other Details:
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Languages: eng Pagination: 261-3 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Acute Disease Complement C3 / metabolism* Complement C4 / metabolism* Hemolysis Humans Pancreatitis / etiology, immunology* Prognosis |
| Chemical | |
Reg. No./Substance:
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0/Complement C3; 0/Complement C4 |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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