| Serum complement (C3, C4) levels in patients with acute myocardial infarction and angina pectoris. | |
| | |
MedLine Citation:
|
PMID: 18783065 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
Serum complement (C3, C4) levels in Libyan patients with acute myocardial infarction (AMI; 31 patients) and angina pectoris (AP; 11 patients) at the 1st day and 7th day of attack were estimated. A group of 26 healthy Libyans were taken as control subjects (CS). Serum C3 and C4 levels (mean +/- SD, mg/dl) were elevated at the 1st day in AMI as well as AP patients (C3 --> AMI1: 154.0 +/- 28.5, AP1: 152.0 +/- 45.0, CS: 132.0 +/- 8.0, ANOVA: p = 0.0072; C4 --> AMII1: 38 +/- 13, AP1: 37 +/- 17, CS: 29 +/- 6, ANOVA: p = 0.0160). No significant differences for the elevated C3 and C4 levels at the 1st day were observed between the two diseases groups (AMI1 vs AP1 --> C3: p = 0.879, C4: p = 0.818). At the 7th day, C3 and C4 levels were further elevated in AMI, while they remained at the similar elevated levels in AP (C3 --> AMI 7: 173.1 +/- 28.0, AP 7: 149.0 +/- 41.0, CS: 132.0 +/- 8.0, ANOVA: p = 0.0000; C4 --> AMI 7: 46.0 +/- 7.0, AP 7: 36.0 +/- 15.0, CS: 29.0 +/- 6.0, ANOVA: p = 0.0000). Again, no significance differences for the raised C3 and C4 levels at the 7th day was observed between AMI and AP patients (AMI 7 vs AP 7 --> C3: P = 0.059, C4: p = 0.06). The C3 elevation showed significant positive correlation in AMI group (r = 0.522, p = 0.003) while it was insignificant in AP patients (r = 0.037, p = 0.915). Regarding C4 levels, it was significantly correlated in AMI (r = 0.483, p = 0.006), and in AP, although it was positively correlated (r = 0.656, P = 0.028) the observed difference was not significant (t = 0.29, p = 0.778). In conclusion, serum C3 and C4 levels were more profoundly elevated in AMI compared to AP patients suggestive of an acute phase and inflammatory response. |
| | |
Authors:
|
A S M Giasuddin; Jamila M ElMahdawi; Fakhri M ElHassadi |
Related Documents
:
|
21200185 - Long-term follow-up of upper and lower extremity vasculitis related to giant cell arter... 17650455 - Antibodies against the cub1-2 domains of adamts13 in a patient with benign monoclonal g... 12022435 - Angiographic and immunologic studies in acute necrotizing jejunoileitis. 605915 - Activation of protein mediators of inflammation and evidence for endotoxemia in borreli... 19184605 - The role of transthoracic echocardiography in embolic acute limb ischaemia. 18664075 - Neuropsychiatric involvement in juvenile systemic lupus erythematosus. |
Publication Detail:
|
Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
|
Title: Bangladesh Medical Research Council bulletin Volume: 33 ISSN: 0377-9238 ISO Abbreviation: Bangladesh Med Res Counc Bull Publication Date: 2007 Dec |
Date Detail:
|
Created Date: 2008-09-11 Completed Date: 2008-10-17 Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 7607686 Medline TA: Bangladesh Med Res Counc Bull Country: Bangladesh |
Other Details:
|
Languages: eng Pagination: 98-102 Citation Subset: IM |
Affiliation:
|
Department of Laboratory Medicine, Al-Arab Medical University, Benghazi, Libya. asmgias@proshikanet.com |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Adult Aged Aged, 80 and over Angina Pectoris / blood*, physiopathology Case-Control Studies Complement C3 / analysis* Complement C4 / analysis* Complement Hemolytic Activity Assay Female Health Surveys Humans Libya Male Middle Aged Myocardial Infarction / blood*, physiopathology Questionnaires Risk Factors |
| Chemical | |
Reg. No./Substance:
|
0/Complement C3; 0/Complement C4 |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: A modified formula for defining tissue phantom ratio of photon beams.
Next Document: Seropositivity and pattern of viral hepatitis in clinically suspected cases of hepatitis in Dhaka ci...