Document Detail

Serum cholesterol reduction and cholesterol absorption inhibition in CaCo-2 cells by a soyprotein peptic hydrolyzate.
MedLine Citation:
PMID:  9058976     Owner:  NLM     Status:  MEDLINE    
The serum cholesterol level in rats was significantly decreased in a group fed on a soyprotein peptic hydrolyzate (SPH) when compared with a group fed on a casein tryptic hydrolyzate (CTH). The fecal excretion of total steroids was significantly greater with rats fed on the SPH diet when compared with the CTH diet. The results of CaCo-2 studies clearly suggest that the suppression of cholesterol absorption in the intestinal epithelia is part of the mechanism for the hypocholesterolemic action induced by SPH.
S Nagaoka; T Awano; N Nagata; M Masaoka; G Hori; K Hashimoto
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Bioscience, biotechnology, and biochemistry     Volume:  61     ISSN:  0916-8451     ISO Abbreviation:  Biosci. Biotechnol. Biochem.     Publication Date:  1997 Feb 
Date Detail:
Created Date:  1997-04-11     Completed Date:  1997-04-11     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  9205717     Medline TA:  Biosci Biotechnol Biochem     Country:  JAPAN    
Other Details:
Languages:  eng     Pagination:  354-6     Citation Subset:  B    
Department of Food Science, Faculty of Agriculture, Gifu University, Japan.
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MeSH Terms
Anticholesteremic Agents / chemistry,  pharmacology*
Caco-2 Cells
Cholesterol / metabolism*
Protein Hydrolysates / pharmacology*
Rats, Wistar
Soybean Proteins / chemistry,  pharmacology*
Soybeans / metabolism
Reg. No./Substance:
0/Anticholesteremic Agents; 0/Protein Hydrolysates; 0/Soybean Proteins; 57-88-5/Cholesterol

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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