Document Detail

Serum calciotropic hormone levels, and dental fluorisis in children exposed to different concentrations of fluoride and iodine in drinking water.
MedLine Citation:
PMID:  20368085     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: High fluoride exposure can result in dental fluorosis. Fluoride and iodine are coexistent in the drinking water of areas in China and may affect the prevalence of dental fluorosis and osteogenesis. The aim of this study was to investigate the relationship between serum calciotropic hormone level, and dental fluorisis in children exposed to different concentrations of fluoride and iodine in drinking water. METHODS: A pilot study was conducted in three villages located in the Kaifeng and Tongxu counties of Henan Province, China in 2006. Children aged 8 to 12 years, born and raised in the three villages were recruited. The fluoride levels in the samples of urine from these children were detected by fluoride ion selective electrode. Calcitonin and osteocalcin levels in the serum, and serum calcium were measured by radioimmunassay and flame atomic absorption spectrometry, respectively. RESULTS: Fluoride levels in urine were significantly lower in children from control area (CA) as compared with those from the high fluoride & iodine areas (HFIA) and the high fluoride area (HFA) (P < 0.05 respectively), and no statistically significant difference was found between the children from HFIA and HFA. Additionally, calcitonin levels in the serum were significantly lower in children from CA and HFA as compared with that from HFIA (P < 0.05 respectively), and osteocalcin levels in the serum was lower in children from CA than those from HFIA (P < 0.05). No statistically significant difference in serum osteocalcin concentrations was found between children from HFA and HFIA. CONCLUSION: This study provides an evidence that iodine exposure may modify the serum calciotropic hormone levels related to fluorine exposure.
Yue Ba; Jiang-yuan Zhu; Yue-jin Yang; Bo Yu; Hui Huang; Gang Wang; Li-jun Ren; Xue-min Cheng; Liu-xin Cui; Ya-wei Zhang
Related Documents :
19290905 - Traumatic dental injuries of permanent incisors in 11- to 13-year-old south african sch...
3467445 - Timing of tooth emergence. a prospective longitudinal study of swedish urban children f...
12834385 - Salivary ph changes during soft drinks consumption in children.
2019085 - Results after 1 year of non-operative occlusal caries treatment of erupting permanent f...
16045255 - The strength of children's knowledge of the role of root morphemes in the spelling of d...
21566305 - Accuracy of cystosonography in the diagnosis of vesicourethral reflux in children.
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Chinese medical journal     Volume:  123     ISSN:  0366-6999     ISO Abbreviation:  Chin. Med. J.     Publication Date:  2010 Mar 
Date Detail:
Created Date:  2010-04-06     Completed Date:  2010-06-29     Revised Date:  2010-09-14    
Medline Journal Info:
Nlm Unique ID:  7513795     Medline TA:  Chin Med J (Engl)     Country:  China    
Other Details:
Languages:  eng     Pagination:  675-9     Citation Subset:  IM    
Department of Environmental Health, Zhengzhou University School of Public Health, Zhengzhou, Henan 450001, China.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Calcitonin / blood*
Fluorides / administration & dosage*
Fluorosis, Dental / epidemiology*
Iodine / administration & dosage*
Osteocalcin / blood*
Pilot Projects
Water Supply / analysis*
Reg. No./Substance:
0/Fluorides; 104982-03-8/Osteocalcin; 7553-56-2/Iodine; 9007-12-9/Calcitonin

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Diagnostic value of dual-source CT in Kawasaki disease.
Next Document:  Correction of severe post-traumatic kyphosis by posterior vertebra column resection.