Document Detail


Serum biomarkers for predicting pregnancy outcome in women undergoing IVF: human chorionic gonadotropin, progesterone, and inhibin A level at 11 days post-ET.
MedLine Citation:
PMID:  22563548     Owner:  NLM     Status:  PubMed-not-MEDLINE    
Abstract/OtherAbstract:
OBJECTIVE: This study was performed to assess the prognostic value of serum hCG, progesterone, and inhibin A levels measured at 11 days post-ET for predicting pregnancy outcome in women participating in IVF.
METHODS: Between May 2005 and April 2008, sera were obtained from 70 infertile women who underwent IVF-ET at 11 days post-ET and stored. HCG, progesterone, and inhibin A levels were measured by commercial enzyme-linked immunosorbent assay kits. The predictive accuracy of hCG, progesterone, and inhibin A levels for establishment of intrauterine pregnancy and ongoing pregnancy was calculated by receiver-operating characteristic curve analysis.
RESULTS: For the prediction of intrauterine and ongoing pregnancy, serum hCG was better than progesterone and inhibin A. The predictive performance of progesterone and inhibin A was similar. The serum progesterone and inhibin A levels were significantly correlated each other (r=0.915, p=0.010).
CONCLUSION: A single measurement of the serum hCG level is sufficient to predict pregnancy outcome in IVF-ET patients.
Authors:
Jee Hyun Kim; Mi Sun Shin; Gwang Yi; Byung Chul Jee; Jung Ryeol Lee; Chang Suk Suh; Seok Hyun Kim
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Publication Detail:
Type:  Journal Article     Date:  2012-03-31
Journal Detail:
Title:  Clinical and experimental reproductive medicine     Volume:  39     ISSN:  2233-8241     ISO Abbreviation:  Clin Exp Reprod Med     Publication Date:  2012 Mar 
Date Detail:
Created Date:  2012-05-07     Completed Date:  2012-08-23     Revised Date:  2013-05-29    
Medline Journal Info:
Nlm Unique ID:  101563916     Medline TA:  Clin Exp Reprod Med     Country:  Korea (South)    
Other Details:
Languages:  eng     Pagination:  28-32     Citation Subset:  -    
Affiliation:
Department of Obstetrics and Gynecology, Seoul National University Bundang Hospital, Seongnam, Korea.
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