| Serum bile acids in patients with hyperlipidaemia. | |
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MedLine Citation:
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PMID: 627619 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Individual serum bile acids were analysed by an improved gas liquid chromatography method in 12 patients with primary hyperlipidaemia. Total serum bile acid concentrations were raised in 10 subjects. Ursodeoxycholic acid was found in all 12 patients. It was present in significantly greater concentrations, accounted for a greater proportion of the total serum bile acids, and occurred more frequently than in patients with various forms of hepatobiliary disease. Patients with hyperlipidaemia had proportionately less deoxycholic acid than controls but more than patients with liver disease. There was proportionately less chenodeoxycholic acid in patients with hypercholesterolaemia, in whom the primary bile acid ratio was raised. |
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Authors:
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C R Pennington; P E Ross; M C Bateson; I A Bouchier |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Journal of clinical pathology Volume: 31 ISSN: 0021-9746 ISO Abbreviation: J. Clin. Pathol. Publication Date: 1978 Jan |
Date Detail:
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Created Date: 1978-04-26 Completed Date: 1978-04-26 Revised Date: 2009-11-18 |
Medline Journal Info:
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Nlm Unique ID: 0376601 Medline TA: J Clin Pathol Country: ENGLAND |
Other Details:
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Languages: eng Pagination: 58-62 Citation Subset: AIM; IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Bile Acids and Salts
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blood* Chenodeoxycholic Acid / blood Cholic Acids / blood Deoxycholic Acid / analogs & derivatives, blood Humans Hyperlipidemias / blood* Liver Diseases / blood |
| Chemical | |
Reg. No./Substance:
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0/Bile Acids and Salts; 0/Cholic Acids; 474-25-9/Chenodeoxycholic Acid; 83-44-3/Deoxycholic Acid |
| Comments/Corrections | |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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