| Serum bile acids in newborns and children. | |
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MedLine Citation:
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PMID: 7454436 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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A specific and sensitive radioimmunoassay for cholic, chenodeoxycholic, and lithocholic acid conjugates and for sulfolithocholylglycine was used to measure serum bile acids (BA) in infants and children. Elevated cholic and chenodeoxycholic acid values were observed in the first year of life in fasting infants. Newborn babies presented high levels of primary BA not correlated with those of the mothers. In premature newborn babies who had not yet been fed, meal induced a considerable reduction in the primary BA levels in serum. In normally fed babies, meal induced a significant increase in the primary BA levels in serum. These data suggest a progressive maturity throughout the first year of life of the serum BA determinants, i.e., gallbladder emptying, intestinal motility and absorption, and hepatic uptake. |
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Authors:
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L Barbara; R Lazzari; A Roda; R Aldini; D Festi; C Sama; A M Morselli; A Collina; F Bazzoli; G Mazzella; E Roda |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Pediatric research Volume: 14 ISSN: 0031-3998 ISO Abbreviation: Pediatr. Res. Publication Date: 1980 Nov |
Date Detail:
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Created Date: 1981-03-27 Completed Date: 1981-03-27 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 0100714 Medline TA: Pediatr Res Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 1222-5 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Bile Acids and Salts
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blood* Chenodeoxycholic Acid / blood Child Child, Preschool Cholic Acids / blood Eating Fasting Female Glycocholic Acid / analogs & derivatives, blood Humans Infant Infant, Newborn Infant, Premature Lithocholic Acid / analogs & derivatives, blood Male |
| Chemical | |
Reg. No./Substance:
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0/Bile Acids and Salts; 0/Cholic Acids; 15324-64-8/sulfolithocholylglycine; 434-13-9/Lithocholic Acid; 474-25-9/Chenodeoxycholic Acid; 475-31-0/Glycocholic Acid |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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