Document Detail


Serum ascorbic acid in patients undergoing chronic hemodialysis.
MedLine Citation:
PMID:  6613689     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Serum presupplementation ascorbic acid levels were subnormal in 8 out of 10 patients undergoing chronic hemodialysis with capillary film and capillary flow dialyzers, the mean duration of treatment being 11 months. Supplementation with 100 mg ascorbic acid daily for two weeks raised the ascorbic acid values to normal in 9 out of 10 patients. After supplementation with 500 mg daily, all patients had ascorbic acid levels exceeding the normal upper limit, and 3 of them had gastrointestinal side-effects. The mean blood pH value, measured in 24 patients on chronic hemodialysis, showed a significant, though slight, decrease during supplementation with 500 mg daily as compared with the mean presupplementation value, but no statistically significant changes were observed in blood bicarbonate, base excess or PCO2 values.
Authors:
A Pönkä; B Kuhlbäck
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Publication Detail:
Type:  Clinical Trial; Controlled Clinical Trial; Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Acta medica Scandinavica     Volume:  213     ISSN:  0001-6101     ISO Abbreviation:  Acta Med Scand     Publication Date:  1983  
Date Detail:
Created Date:  1983-10-08     Completed Date:  1983-10-08     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0370330     Medline TA:  Acta Med Scand     Country:  SWEDEN    
Other Details:
Languages:  eng     Pagination:  305-7     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Acid-Base Equilibrium / drug effects
Adolescent
Adult
Aged
Ascorbic Acid / administration & dosage,  blood
Ascorbic Acid Deficiency / etiology*
Humans
Hydrogen-Ion Concentration
Male
Middle Aged
Renal Dialysis / adverse effects*
Chemical
Reg. No./Substance:
50-81-7/Ascorbic Acid

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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