Document Detail


Serum apolipoprotein levels of psoriatic patients with normal serum lipid levels.
MedLine Citation:
PMID:  11360555     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
OBJECTIVE: Recent studies indicated that incidence of occlusive cardiovascular diseases increased in psoriasis. Changes of serum lipid metabolism may be the cause. Apolipoproteins play a central role in lipoprotein metabolism in serum. The measurement of serum apo levels may reveal the characteristics of lipoprotein metabolism in serum in patients with psoriasis and may help to find an answer to the cause of the high incidence of occlusive cardiovascular diseases in psoriasis. METHOD: The apo levels of 31 patients with psoriasis vulgaris and 31 sex- and age-matched healthy individuals with normal serum lipid levels were measured by radial immunodiffusion assay. RESULTS: The apo C III (t = 2.44, P < 0.05) and apo E (t = 2.12, P < 0.05) of psoriatic group elevated significantly. The apo C III (t = 2.77, P < 0.01) of patients less than 40-year-old and apoE (t = 2.91, P < 0.01) of male patients elevated significantly. CONCLUSION: Abnormal metabolism of lipoprotein in serum exist in psoriasis, especially in male patients and/or patients less than 40 years old.
Authors:
T Xiao; C Yang; Y Xiao; F Song
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Chinese medical sciences journal = Chung-kuo i hsüeh k'o hsüeh tsa chih / Chinese Academy of Medical Sciences     Volume:  12     ISSN:  1001-9294     ISO Abbreviation:  Chin. Med. Sci. J.     Publication Date:  1997 Dec 
Date Detail:
Created Date:  2001-05-21     Completed Date:  2001-06-14     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  9112559     Medline TA:  Chin Med Sci J     Country:  China    
Other Details:
Languages:  eng     Pagination:  224-8     Citation Subset:  IM    
Affiliation:
Clinical Immune Laboratory, Department of Dermatology, First Hospital, China Medical University, Shenyang 110001.
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MeSH Terms
Descriptor/Qualifier:
Adult
Age Factors
Aged
Apolipoprotein C-III
Apolipoproteins C / blood*
Apolipoproteins E / blood*
Female
Humans
Male
Middle Aged
Psoriasis / blood*
Sex Factors
Chemical
Reg. No./Substance:
0/Apolipoprotein C-III; 0/Apolipoproteins C; 0/Apolipoproteins E

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