Document Detail

Serum apolipoprotein levels of psoriatic patients with normal serum lipid levels.
MedLine Citation:
PMID:  11360555     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: Recent studies indicated that incidence of occlusive cardiovascular diseases increased in psoriasis. Changes of serum lipid metabolism may be the cause. Apolipoproteins play a central role in lipoprotein metabolism in serum. The measurement of serum apo levels may reveal the characteristics of lipoprotein metabolism in serum in patients with psoriasis and may help to find an answer to the cause of the high incidence of occlusive cardiovascular diseases in psoriasis. METHOD: The apo levels of 31 patients with psoriasis vulgaris and 31 sex- and age-matched healthy individuals with normal serum lipid levels were measured by radial immunodiffusion assay. RESULTS: The apo C III (t = 2.44, P < 0.05) and apo E (t = 2.12, P < 0.05) of psoriatic group elevated significantly. The apo C III (t = 2.77, P < 0.01) of patients less than 40-year-old and apoE (t = 2.91, P < 0.01) of male patients elevated significantly. CONCLUSION: Abnormal metabolism of lipoprotein in serum exist in psoriasis, especially in male patients and/or patients less than 40 years old.
T Xiao; C Yang; Y Xiao; F Song
Related Documents :
3043725 - An introduction to clinical epidemiology.
3887825 - High prevalence of cardiovascular diseases and enhanced activity of the renin-angiotens...
903165 - Esterase d phenotypes in psoriasis vulgaris, atopic diseases and healthy controls.
7054305 - Role of the microcirculation in the treatment and pathogenesis of psoriasis.
6170755 - Inosiplex: a novel treatment in rheumatoid arthritis?
25012695 - Development and validation of a new screening questionnaire for dysphagia in early stag...
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Chinese medical sciences journal = Chung-kuo i hsüeh k'o hsüeh tsa chih / Chinese Academy of Medical Sciences     Volume:  12     ISSN:  1001-9294     ISO Abbreviation:  Chin. Med. Sci. J.     Publication Date:  1997 Dec 
Date Detail:
Created Date:  2001-05-21     Completed Date:  2001-06-14     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  9112559     Medline TA:  Chin Med Sci J     Country:  China    
Other Details:
Languages:  eng     Pagination:  224-8     Citation Subset:  IM    
Clinical Immune Laboratory, Department of Dermatology, First Hospital, China Medical University, Shenyang 110001.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Age Factors
Apolipoprotein C-III
Apolipoproteins C / blood*
Apolipoproteins E / blood*
Middle Aged
Psoriasis / blood*
Sex Factors
Reg. No./Substance:
0/Apolipoprotein C-III; 0/Apolipoproteins C; 0/Apolipoproteins E

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Changes on receptor expression and production of interleukin-2 in circulating lymphocyte population ...
Next Document:  The development of monoclonal antibody against rhTNF and its curative effects on E. coli infected mi...