Document Detail

Serum angiotensin-converting enzyme activity in pre-eclamptic pregnancy: evidence for a relative hypermesorACEemia.
MedLine Citation:
PMID:  1965644     Owner:  NLM     Status:  MEDLINE    
The circadian rhythm of serum angiotensin-converting enzyme (ACE) activity was investigated in pregnant women with normal and pre-eclamptic gestation. The chronobiological approach was able to document the occurrence of a circadian rhythm for serum ACE activity in normal pregnancy. Such a rhythm is characterized by a decreased mesor and amplitude and a shifted crest. The circadian rhythm for serum ACE activity was not detectable in pre-eclamptic pregnancy. Such an abrogation is accompanied by a negligible decrease of mesor suggesting the occurrence of a relative hyperACEemia. This disorder could play a role in pregnancy-induced hypertension.
P Cugini; C Letizia; L Di Palma; P Battisti; D Caserta; M Moscarini; D Scavo
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Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  Enzyme     Volume:  43     ISSN:  0013-9432     ISO Abbreviation:  Enzyme     Publication Date:  1990  
Date Detail:
Created Date:  1991-07-05     Completed Date:  1991-07-05     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  1262265     Medline TA:  Enzyme     Country:  SWITZERLAND    
Other Details:
Languages:  eng     Pagination:  113-21     Citation Subset:  IM    
I Patologia Medica, University of Rome La Sapienza, Italy.
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MeSH Terms
Blood Pressure
Circadian Rhythm*
Menstrual Cycle / blood
Peptidyl-Dipeptidase A / blood*
Pre-Eclampsia / enzymology*
Pregnancy / blood*
Reg. No./Substance:

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