Document Detail

Serum angiotensin converting enzyme (ACE) in silicosis.
MedLine Citation:
PMID:  6092123     Owner:  NLM     Status:  MEDLINE    
Circulating Angiotensin Converting Enzyme (ACE) level, chest X-rays and respiratory function tests were determined in 76 male patients with silicosis. Mean serum ACE in the patients was significantly higher than in 30 healthy controls (129.8 +/- 4 U/ml and 92.4 +/- 22.7 respectively), although individual values were in the normal range in about half of the patients. Enzyme levels were independent of silica dust exposure, X-ray changes, functional lung impairment, age, smoking habits, and presence of chronic obstructive pulmonary disease. However, patients with more severe radiological changes tended to have lower ACE values. Our data confirm that serum ACE level is frequently raised in silicosis, but does not give further information in the evaluation of the disease.
C Bucca; F Veglio; G Rolla; M Cacciabue; C Cicconi; M Ossola; A Nuzzi; G Avolio; A Angeli
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  European journal of respiratory diseases     Volume:  65     ISSN:  0106-4339     ISO Abbreviation:  Eur J Respir Dis     Publication Date:  1984 Oct 
Date Detail:
Created Date:  1984-12-10     Completed Date:  1984-12-10     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  8006891     Medline TA:  Eur J Respir Dis     Country:  DENMARK    
Other Details:
Languages:  eng     Pagination:  477-80     Citation Subset:  IM    
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MeSH Terms
Middle Aged
Peptidyl-Dipeptidase A / blood*
Respiratory Function Tests
Silicosis / diagnosis,  enzymology*,  radiography
Reg. No./Substance:

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