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Serum adiponectin levels are significantly reduced during the second half of normal pregnancy.
MedLine Citation:
PMID:  21995147     Owner:  NLM     Status:  In-Process    
Abstract/OtherAbstract:
PURPOSE: To demonstrate the physiologic changes in adiponectin levels during the first vs second half of pregnancy.
METHODS: Sixty-six females with uncomplicated pregnancies and normal pre-gestational BMI had serum adiponectin levels obtained at various gestational ages. Thirty-one samples were obtained during the first half of their pregnancy vs 35 in the second half. Thirty-three healthy non-pregnant females with comparable ages and BMI were controls.
RESULTS: Mean adiponectin levels were 9.55 microg/dl (95% CI 8.2-10.77) vs 9.48 microg/dl (95% CI 8.44-10.66) in the control group in the first half of pregnancy (p = NS). We noted a 21% reduction in mean adiponectin levels (7.51 microg/dl) during the second half of pregnancy (p = 0.03) compared to the first half of pregnancy.
CONCLUSION: Early pregnancy does not affect adiponectin levels. However, there is a significant reduction in adiponectin levels during the second half of pregnancy.
Authors:
H Elshoreya; F Steinberg; R Perry; C Hansen; B Milcareck; S Elkouachi; J H Check
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Clinical and experimental obstetrics & gynecology     Volume:  38     ISSN:  0390-6663     ISO Abbreviation:  Clin Exp Obstet Gynecol     Publication Date:  2011  
Date Detail:
Created Date:  2011-10-14     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7802110     Medline TA:  Clin Exp Obstet Gynecol     Country:  Italy    
Other Details:
Languages:  eng     Pagination:  211-3     Citation Subset:  IM    
Affiliation:
The University of Medicine and Dentistry of New Jersey, Robert Wood Johnson Medical School at Camden, Cooper Hospital/University Medical Center, Department of Obstetrics and Gynecology, Division of Reproductive Endocrinology & Infertility, Camden, NJ, USA.
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