| Serum acute phase reactants in necrotizing enterocolitis. | |
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MedLine Citation:
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PMID: 2447744 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The serum acute phase reactants, C-reactive protein (CRP) and orosomucoid, rose significantly within 24 to 48 hours of presentation in infants with definite necrotizing enterocolitis (NEC) compared with the levels in infants with symptoms who tolerated early reintroduction of enteral feeds. A serum CRP value greater than 10 mg/l within 48 hours identified infants with definite NEC with a 92% sensitivity and an 81% specificity. Serum CRP values remained elevated at 7 to 10 days in 4 infants with late septicaemia and in 4 of 5 infants with abscess or early stricture requiring surgery. Serum acute phase reactants are a potentially valuable adjunct to clinical assessment in the management of infants with suspected NEC. |
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Authors:
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D Isaacs; J North; D Lindsell; A R Wilkinson |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Acta paediatrica Scandinavica Volume: 76 ISSN: 0001-656X ISO Abbreviation: Acta Paediatr Scand Publication Date: 1987 Nov |
Date Detail:
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Created Date: 1988-02-23 Completed Date: 1988-02-23 Revised Date: 2009-11-11 |
Medline Journal Info:
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Nlm Unique ID: 0000211 Medline TA: Acta Paediatr Scand Country: SWEDEN |
Other Details:
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Languages: eng Pagination: 923-7 Citation Subset: IM |
Affiliation:
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Department of Paediatrics, John Radcliffe Hospital, Headington, Oxford, UK. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Acute-Phase Proteins
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blood* C-Reactive Protein / blood Enterocolitis, Pseudomembranous / blood*, complications, diagnosis Humans Infant, Newborn Orosomucoid / blood |
| Chemical | |
Reg. No./Substance:
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0/Acute-Phase Proteins; 0/Orosomucoid; 9007-41-4/C-Reactive Protein |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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