Document Detail

Serum acid phosphatase can be a useful tumour marker for giant cell tumour of bone.
MedLine Citation:
PMID:  19319545     Owner:  NLM     Status:  In-Process    
INTRODUCTION: The purpose of this study was to elucidate the clinical significance of acid phosphatase in giant cell tumour of bone. PATIENTS AND METHODS: Serum acid phosphatase levels were measured in 32 patients with this tumour both preoperatively and postoperatively. RESULTS: Serum acid phosphatase value before surgery was high in 15 patients, whereas it was within normal limits in 17 patients. The serum acid phosphatase values of all the 15 patients with high preoperative serum level fell within normal limits postoperatively. In the remaining 17 patients in whom preoperative serum acid phosphatase values were within normal limits, postoperative serum acid phosphatase levels were lower than that of preoperative ones in all the patients. In addition, there was a statistically significant positive correlation between the tumour volume and the preoperative serum acid phosphatase level. CONCLUSION: It is concluded that serum acid phosphatase is a useful tumour marker for giant cell tumour of bone.
Takahiro Goto; Hirotaka Kawano; Toru Akiyama; Yusuke Shinoda; Tomotake Okuma; Hiroshi Kobayashi; Tetsuo Nemoto; Nobuaki Funata
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't     Date:  2009-03-25
Journal Detail:
Title:  Archives of orthopaedic and trauma surgery     Volume:  129     ISSN:  1434-3916     ISO Abbreviation:  Arch Orthop Trauma Surg     Publication Date:  2009 Dec 
Date Detail:
Created Date:  2009-11-09     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9011043     Medline TA:  Arch Orthop Trauma Surg     Country:  Germany    
Other Details:
Languages:  eng     Pagination:  1641-4     Citation Subset:  IM    
Department of Orthopaedic Surgery and Musculoskeletal Oncology, Tokyo Metropolitan Komagome Hospital, 3-18-22 Hon-Komagome, Bunkyo-ku, Tokyo, 113-8677, Japan.
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