| Serum Uric Acid: A Marker of Metabolic Syndrome and Subclinical Atherosclerosis in Korean Men. | |
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MedLine Citation:
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PMID: 22007031 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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Serum uric acid (SUA) is a potential risk factor for atherosclerosis. We assessed the relationship between SUA and subclinical atherosclerosis in Korean men (n = 3010). Multidetector computed tomography (MDCT) and ultrasonographic measurements of coronary artery calcification (CAC) and carotid intima-media thickness (cIMT), respectively, are markers of subclinical atherosclerosis. Odds ratios (ORs) of CAC score and cIMT across SUA levels were 1.101 (P = .046) and 1.266 (P = .002), respectively, after adjustment for several variables. The independent association between CAC and cIMT was observed (OR = 1.231, P < .001). Serum uric acid was independently associated with metabolic syndrome (MetS) with an OR of 1.415 (P < .001). Metabolic syndrome was only independently associated with cIMT, with an OR of 2.103 (P = .003). High-sensitivity C-reactive protein was positively correlated with SUA (r = .125, P < .001). Serum uric acid level is independently associated with CAC, cIMT, and MetS in Korean men. |
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Authors:
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Zhengyun Zhang; Luqin Bian; Yoonho Choi |
Publication Detail:
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Type: JOURNAL ARTICLE Date: 2011-10-17 |
Journal Detail:
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Title: Angiology Volume: - ISSN: 1940-1574 ISO Abbreviation: - Publication Date: 2011 Oct |
Date Detail:
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Created Date: 2011-10-18 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0203706 Medline TA: Angiology Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Affiliation:
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Shanghai Jiaotong University, Shanghai, China; Sungkyunkwan University School of Medicine, Seoul, South Korea. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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