Document Detail

Serum IL-9 Levels Depend on Allergen Exposure: Preliminary Study.
MedLine Citation:
PMID:  20861646     Owner:  NLM     Status:  In-Data-Review    
Background: Th9 is a new T cell subset characterized by interleukin 9 (IL-9) production. Serum IL-9 levels are related to symptom severity in patients with allergic rhinitis (AR). This study aimed at investigating whether IL-9 may depend on allergen exposure. Methods: 35 AR patients (16 males, mean age 33.2 years) with monosensitization to Parietaria were studied when symptomatic; 38 AR patients (22 males, mean age 30.9 years) with monosensitization to birch were recruited at the same time, but were symptom free. Serum IL-9 was assayed in all patients. Results: Patients with Parietaria allergy and exposed to allergen had higher serum IL-9 levels than patients with birch allergy and not exposed to allergen (p < 0.05). Conclusions: This preliminary study shows that serum IL-9 levels may depend on allergen exposure: symptomatic patients with pollen-induced AR, evaluated during the pollen season, have higher values than patients studied outside the pollen season and without symptoms.
Giorgio Ciprandi; Mara De Amici; Anna Maria Castellazzi; Maria Angela Tosca; Gianluigi Marseglia
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Publication Detail:
Type:  Journal Article     Date:  2010-09-21
Journal Detail:
Title:  International archives of allergy and immunology     Volume:  154     ISSN:  1423-0097     ISO Abbreviation:  Int. Arch. Allergy Immunol.     Publication Date:  2011  
Date Detail:
Created Date:  2011-02-21     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9211652     Medline TA:  Int Arch Allergy Immunol     Country:  Switzerland    
Other Details:
Languages:  eng     Pagination:  246-8     Citation Subset:  IM    
Copyright Information:
Copyright © 2010 S. Karger AG, Basel.
Department of Internal Medicine, Azienda Ospedaliera Universitaria San Martino, University of Genoa, Genoa, Italy.
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