| Serum IL-9 Levels Depend on Allergen Exposure: Preliminary Study. | |
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MedLine Citation:
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PMID: 20861646 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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Background: Th9 is a new T cell subset characterized by interleukin 9 (IL-9) production. Serum IL-9 levels are related to symptom severity in patients with allergic rhinitis (AR). This study aimed at investigating whether IL-9 may depend on allergen exposure. Methods: 35 AR patients (16 males, mean age 33.2 years) with monosensitization to Parietaria were studied when symptomatic; 38 AR patients (22 males, mean age 30.9 years) with monosensitization to birch were recruited at the same time, but were symptom free. Serum IL-9 was assayed in all patients. Results: Patients with Parietaria allergy and exposed to allergen had higher serum IL-9 levels than patients with birch allergy and not exposed to allergen (p < 0.05). Conclusions: This preliminary study shows that serum IL-9 levels may depend on allergen exposure: symptomatic patients with pollen-induced AR, evaluated during the pollen season, have higher values than patients studied outside the pollen season and without symptoms. |
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Authors:
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Giorgio Ciprandi; Mara De Amici; Anna Maria Castellazzi; Maria Angela Tosca; Gianluigi Marseglia |
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Publication Detail:
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Type: Journal Article Date: 2010-09-21 |
Journal Detail:
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Title: International archives of allergy and immunology Volume: 154 ISSN: 1423-0097 ISO Abbreviation: Int. Arch. Allergy Immunol. Publication Date: 2011 |
Date Detail:
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Created Date: 2011-02-21 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9211652 Medline TA: Int Arch Allergy Immunol Country: Switzerland |
Other Details:
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Languages: eng Pagination: 246-8 Citation Subset: IM |
Copyright Information:
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Copyright © 2010 S. Karger AG, Basel. |
Affiliation:
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Department of Internal Medicine, Azienda Ospedaliera Universitaria San Martino, University of Genoa, Genoa, Italy. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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