| Serum HDL, LDL and total cholesterol in patients with late-life onset of Alzheimer's disease versus vascular dementia. | |
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MedLine Citation:
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PMID: 20055246 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Patients with cerebrovascular risk factors are nowadays recognized as being at an increased risk of developing cognitive decline of both types. In this pilot study, we evaluated the levels of cholesterol (total, HDL, LDL) in patients with both vascular dementia (VD) and Alzheimer's type of dementia (AD). Cognitive decline was assessed using Mini Mental State Examination (MMSE) as a standardized method. The study included 66 patients diagnosed with dementia. AD was diagnosed in 43 patients (22 male and 21 female) mean age (+/- SD) 72.79 +/- 8.19 years and VD in 23 patients (mean age +/- SD, 77.43 +/- 7.58 years). In AD group, 18 patients had cholesterol values within the normal range, whereas 25 patients had elevated levels of cholesterol. The mean value of total plasma cholesterol was 5.39 (SD = 1.05), LDL cholesterol 3.33 (SD = 0.95) and HDL cholesterol 1.41 (SD = 0.34). In VD group, 11 patients had cholesterol values within the normal range, whereas 12 patients had elevated levels of cholesterol. In this group, the mean value of total plasma cholesterol was 5.78 (SD = 1.06), HDL cholesterol 1.44 (SD = 0.57) and LDL cholesterol 3.72 (SD = 0.85). Total cholesterol, LDL cholesterol and HDL cholesterol levels were higher in the group of patients with VD, however, the difference was not statistically significant. |
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Authors:
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Zlatko Trkanjec; Raphael Béné; Irena Martinić-Popović; Jelena Miljenka Jurasić; Marijana Lisak; Vesna Serić; Vida Demarin |
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Publication Detail:
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Type: Comparative Study; Journal Article |
Journal Detail:
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Title: Acta clinica Croatica Volume: 48 ISSN: 0353-9466 ISO Abbreviation: Acta Clin Croat Publication Date: 2009 Sep |
Date Detail:
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Created Date: 2010-01-08 Completed Date: 2010-01-29 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9425483 Medline TA: Acta Clin Croat Country: Croatia |
Other Details:
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Languages: eng Pagination: 259-63 Citation Subset: IM |
Affiliation:
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University Department of Neurology, Reference Center for Neurovascular Disorders, Ministry of Health and Social Welfare of Republic of Croatia, Sestre milosrdnice University Hospital, Zagreb, Croatia. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Age of Onset Aged Alzheimer Disease / blood*, psychology Cholesterol / blood* Cholesterol, HDL / blood Cholesterol, LDL / blood Cognition Dementia, Vascular / blood*, psychology Female Humans Male |
| Chemical | |
Reg. No./Substance:
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0/Cholesterol, HDL; 0/Cholesterol, LDL; 57-88-5/Cholesterol |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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