Document Detail


Serum Galactomannan and (1->3) β-D-Glucan Assays in Patients with Multiple Myeloma and Waldenstrom's Macroglobulinemia.
MedLine Citation:
PMID:  22170932     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
We assessed the performance of galactomannan and (1→3)-β-D-glucan in 29 serum samples from patients with multiple myeloma and Waldenstrom's macroglobulinemia without invasive fungal disease to address issues of false positivity and uninterpretable results previously reported among patients with these conditions. Galactomannan and (1→3)-β-D-glucan assays were not falsely elevated in any patient. (1→3)-β-D-glucan assay results were uninterpretable in 24% of patients. Patients with IgG >2000 mg/dL had higher odds of uninterpretable (1→3)-β-D-glucan results.
Authors:
Nicolas C Issa; Sophia Koo; Robert C Lynch; Charline Gay; Sarah P Hammond; Lindsey R Baden; Irene M Ghobrial; Malcolm A Finkelman; Francisco M Marty
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2011-12-14
Journal Detail:
Title:  Journal of clinical microbiology     Volume:  -     ISSN:  1098-660X     ISO Abbreviation:  -     Publication Date:  2011 Dec 
Date Detail:
Created Date:  2011-12-15     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7505564     Medline TA:  J Clin Microbiol     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Affiliation:
Division of Infectious Diseases, Brigham and Women's Hospital, Boston, Massachusetts.
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