| Serum CK-MB activity during and after aortocoronary bypass surgery. | |
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MedLine Citation:
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PMID: 6977424 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Frequent serum sampling of CK-MB and total CK levels was carried out in 100 patients during and up to 48 hours following aortocoronary bypass surgery. Using an ion exchange chromatography method for CK-MB determination, significantly higher serum CK-MB levels (peak 46.1 +/- 5.2 cf. 31.3 +/- 2.2 u/L), but not total CK levels were present 6 to 16 hours postoperatively in those with new Q waves in the ECG. Serum levels of CK-MB in those patients with uncomplicated surgery were defined. New post-operative Q waves were seen in only one half of cases with frankly abnormal CK-MB curves and seriously underestimated the incidence of perioperative infarction. Peak levels of CK-MB in patients with new Q waves occurred within 16 hours of surgery suggesting that infarction is usually an intraoperative or early post-operative event. |
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Authors:
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B C Morton; F M Smith; D S Ooi; A R Moti; J Quevillon; R C Nair; L R Neri; M T Meuffels; W J Keon |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Clinical biochemistry Volume: 14 ISSN: 0009-9120 ISO Abbreviation: Clin. Biochem. Publication Date: 1981 Dec |
Date Detail:
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Created Date: 1982-05-21 Completed Date: 1982-05-21 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 0133660 Medline TA: Clin Biochem Country: CANADA |
Other Details:
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Languages: eng Pagination: 300-4 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Chromatography, Ion Exchange
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methods Coronary Artery Bypass* Creatine Kinase / blood* Electrocardiography Female Humans Isoenzymes Male Middle Aged Time Factors |
| Chemical | |
Reg. No./Substance:
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0/Isoenzymes; EC 2.7.3.2/Creatine Kinase |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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