Document Detail


Serum anti-müllerian hormone, follicle stimulating hormone and antral follicle count measurement cannot predict pregnancy rates in IVF/ICSI cycles.
MedLine Citation:
PMID:  22492221     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
PURPOSE: To investigate whether serum anti-müllerian hormone (AMH), follicle stimulating hormone (FSH), or antral follicle count (AFC) are predictive for clinical pregnancy in in vitro fertilization (IVF) patients.
METHODS: Serum AMH, inhibin B, FSH, luteinizing hormone (LH), estradiol (E2), prolactin, and thyroid stimulating hormone (TSH) levels and AFC of 189 women under 40 years of age were investigated. Pregnant and non-pregnant women were compared.
RESULTS: Forty-seven (24.8 %) clinical pregnancies were observed in 189 women. There was no significant difference in terms of mean age, duration of infertility, body mass index, AMH, LH, FSH, E2, TSH, Inhibin B, AFC and total oocyte number between women who did and who did not become pregnant. Additionally, there was no significant difference in clinical pregnancy rates between the quartiles of AMH, FSH and AFC. (P values were 0.668, 0.071, and 0.252, respectively.)
CONCLUSION: Serum AMH and FSH, and AFC cannot predict clinical pregnancy in IVF patients under 40; the pregnancy rate tends to increase as AMH increases, although this remains non-significant.
Authors:
Sezai Sahmay; Gökhan Demirayak; Onur Guralp; Pelin Ocal; Levent M Senturk; Engin Oral; Tulay Irez
Publication Detail:
Type:  Journal Article     Date:  2012-04-11
Journal Detail:
Title:  Journal of assisted reproduction and genetics     Volume:  29     ISSN:  1573-7330     ISO Abbreviation:  J. Assist. Reprod. Genet.     Publication Date:  2012 Jul 
Date Detail:
Created Date:  2012-07-23     Completed Date:  2013-01-24     Revised Date:  2013-07-02    
Medline Journal Info:
Nlm Unique ID:  9206495     Medline TA:  J Assist Reprod Genet     Country:  Netherlands    
Other Details:
Languages:  eng     Pagination:  589-95     Citation Subset:  IM    
Affiliation:
Department of Obstetrics and Gynecology, Division of Reproductive Endocrinology, Istanbul University, Cerrahpasa School of Medicine, Istanbul, Turkey.
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MeSH Terms
Descriptor/Qualifier:
Adult
Anti-Mullerian Hormone / blood*
Estradiol / blood
Female
Fertilization in Vitro*
Follicle Stimulating Hormone / blood*
Humans
Inhibins / blood
Luteinizing Hormone / blood
Ovarian Follicle / physiology*
Pregnancy
Pregnancy Rate*
Prolactin / blood
Sperm Injections, Intracytoplasmic*
Thyrotropin / blood
Chemical
Reg. No./Substance:
0/inhibin B; 50-28-2/Estradiol; 57285-09-3/Inhibins; 80497-65-0/Anti-Mullerian Hormone; 9002-62-4/Prolactin; 9002-67-9/Luteinizing Hormone; 9002-68-0/Follicle Stimulating Hormone; 9002-71-5/Thyrotropin
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