Document Detail


Serum 25-hydroxyvitamin D, parathyroid hormone, and their association with metabolic syndrome in Chinese.
MedLine Citation:
PMID:  23340918     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
Increasing evidence suggests that 25-hydroxyvitamin D [25(OH)D] and parathyroid hormone (PTH) levels are associated with metabolic syndrome (MetS). In 2010, we explored the association of serum 25(OH)D and PTH levels with MetS in 1,390 Chinese participants, aged 20-83 years. Anthropometric phenotypes, blood pressure, and the incidence of MetS were evaluated. In addition, serum lipids, 25(OH)D, and PTH were measured. The median concentration of 25(OH)D and PTH were 55.3 nmol/l and 2.8 pmol/l, respectively. The prevalence of vitamin D deficiency (<50 nmol/l) was 39.9 %, with 34.5 % in men and 47.8 % in women. After accounting for confounding factors and serum PTH, a 10 nmol/l higher serum 25(OH)D level was associated with a 10 % lower risk of MetS (OR = 0.90, 95 % CI 0.84-0.96, P = 0.0007). Furthermore, participants with vitamin D sufficiency had a 35 % lower risk of MetS than those with vitamin D deficiency (OR = 0.65, 95 % CI 0.51-0.84, P = 0.0009). PTH was not associated with the risk of MetS after adjustment for confounding factors. These results were confirmed in both men and women. Thus in this cohort of Chinese individuals, vitamin D deficiency is common and optimal vitamin D level is inversely associated with MetS, independent of several confounders and PTH level. The clinical significance of these findings warrants further study.
Authors:
Li-Hua Li; Xue-Yan Yin; Chao-Yong Yao; Xue-Chuang Zhu; Xin-Hua Wu
Related Documents :
23062328 - Racial/ethnic differences in control of cardiovascular risk factors among type 2 diabet...
23341938 - Relationship between insulin resistance and coronary artery calcium in young men and wo...
17242038 - Idiopathic intracranial hypertension and visual function.
23507268 - Risk factors for esrd in individuals with preserved estimated gfr with and without albu...
2522238 - Occupational causes of low-back pain.
23531438 - Comparison of brachial artery vascular responses among postmenopausal women receiving d...
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2013-1-23
Journal Detail:
Title:  Endocrine     Volume:  -     ISSN:  1559-0100     ISO Abbreviation:  Endocrine     Publication Date:  2013 Jan 
Date Detail:
Created Date:  2013-1-23     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9434444     Medline TA:  Endocrine     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Affiliation:
Department of Internal Medicine, Dali University School of Clinical Medicine, Jiashibo Road 32, Dali, 671000, Yunnan, China, lilihuayncn@gmail.com.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Neck dissection after chemoradiotherapy for oropharyngeal and hypopharyngeal cancer: the correlation...
Next Document:  Activation of Si-Si and Si-H bonds at Pt: a catalytic hydrogenolysis of silicon-silicon bonds.