Document Detail

Sertaconazole nitrate cream 2% for the treatment of tinea pedis.
MedLine Citation:
PMID:  19537285     Owner:  NLM     Status:  MEDLINE    
Tinea pedis, both in its acute and chronic phase, is a common skin condition that often is overlooked but can lead to onychomycosis and acute bacterial cellulitis if left untreated. Therefore, aggressive treatment with a topical antifungal agent is warranted. Sertaconazole nitrate cream 2% is a newer imidazole agent that possesses both fungicidal and fungistatic properties to eradicate existing infections. In addition to antifungal properties, it exhibits anti-inflammatory and antipruritic effects. Controlled clinical trials have confirmed its safety, tolerability, and efficacy in participants with tinea pedis. We report 2 patients with chronic tinea pedis of many years' duration and demonstrate the usefulness of sertaconazole nitrate cream 2% in the clinical setting. Tinea pedis was confirmed by results of a potassium hydroxide preparation. Both patients experienced marked improvement by the second week of twice-daily treatment with sertaconazole nitrate cream 2%. Clinical cure was achieved in both patients. These findings suggest that sertaconazole nitrate cream 2% is an effective option for the treatment of tinea pedis.
Bret M Ribotsky
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Publication Detail:
Type:  Case Reports; Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Cutis     Volume:  83     ISSN:  0011-4162     ISO Abbreviation:  Cutis     Publication Date:  2009 May 
Date Detail:
Created Date:  2009-06-19     Completed Date:  2009-08-04     Revised Date:  2013-09-12    
Medline Journal Info:
Nlm Unique ID:  0006440     Medline TA:  Cutis     Country:  United States    
Other Details:
Languages:  eng     Pagination:  274-7     Citation Subset:  IM    
Podiatric Success & Skin Care Research, Boca Raton, Florida, USA.
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MeSH Terms
Administration, Topical
Anti-Inflammatory Agents / administration & dosage*
Antifungal Agents / administration & dosage*
Imidazoles / administration & dosage*
Thiophenes / administration & dosage*
Tinea Pedis / drug therapy*
Treatment Outcome
Reg. No./Substance:
0/Anti-Inflammatory Agents; 0/Antifungal Agents; 0/Imidazoles; 0/Ointments; 0/Thiophenes; 72W71I16EG/sertaconazole

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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