| Sertaconazole nitrate cream 2% for the treatment of tinea pedis. | |
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MedLine Citation:
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PMID: 19537285 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Tinea pedis, both in its acute and chronic phase, is a common skin condition that often is overlooked but can lead to onychomycosis and acute bacterial cellulitis if left untreated. Therefore, aggressive treatment with a topical antifungal agent is warranted. Sertaconazole nitrate cream 2% is a newer imidazole agent that possesses both fungicidal and fungistatic properties to eradicate existing infections. In addition to antifungal properties, it exhibits anti-inflammatory and antipruritic effects. Controlled clinical trials have confirmed its safety, tolerability, and efficacy in participants with tinea pedis. We report 2 patients with chronic tinea pedis of many years' duration and demonstrate the usefulness of sertaconazole nitrate cream 2% in the clinical setting. Tinea pedis was confirmed by results of a potassium hydroxide preparation. Both patients experienced marked improvement by the second week of twice-daily treatment with sertaconazole nitrate cream 2%. Clinical cure was achieved in both patients. These findings suggest that sertaconazole nitrate cream 2% is an effective option for the treatment of tinea pedis. |
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Authors:
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Bret M Ribotsky |
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Publication Detail:
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Type: Case Reports; Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Cutis; cutaneous medicine for the practitioner Volume: 83 ISSN: 0011-4162 ISO Abbreviation: Cutis Publication Date: 2009 May |
Date Detail:
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Created Date: 2009-06-19 Completed Date: 2009-08-04 Revised Date: 2009-11-11 |
Medline Journal Info:
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Nlm Unique ID: 0006440 Medline TA: Cutis Country: United States |
Other Details:
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Languages: eng Pagination: 274-7 Citation Subset: IM |
Affiliation:
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Podiatric Success & Skin Care Research, Boca Raton, Florida, USA. ribotsky@yahoo.com |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Administration, Topical Aged Anti-Inflammatory Agents / administration & dosage* Antifungal Agents / administration & dosage* Female Humans Imidazoles / administration & dosage* Male Ointments Thiophenes / administration & dosage* Tinea Pedis / drug therapy* Treatment Outcome |
| Chemical | |
Reg. No./Substance:
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0/Anti-Inflammatory Agents; 0/Antifungal Agents; 0/Imidazoles; 0/Ointments; 0/Thiophenes; 99592-32-2/sertaconazole |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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