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Sertaconazole 2 % cream vs. hydrocortisone 1% cream in the treatment of seborrheic dermatitis.
MedLine Citation:
PMID:  23210976     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
Abstract Objective: Seborrheic dermatitis (SD) is commonly treated with anti-inflammatory products, including topical corticosteroids. This study was undertaken to compare efficiency of sertaconazole 2 % cream vs. hydrocortisone 1% cream in the treatment of seborrheic dermatitis. Methods: In this clinical trial study, Sixty patients suffering from SD were studied. Thirty patients received local sertoconazole 2% cream and they were recommended to use the cream twice a day and for 4 weeks. In control group thirty patients received hydrocortisone 1% cream twice a day for four weeks. At the beginning of referring and also 2 and 4 weeks after first visit, the patients were examined by a dermatologist to control improvement of clinical symptoms. Results: The mean age of patients was 32.23 ± 12.09. The highest level of satisfaction (90%) was observed 28 days after sertaconazole consumption since it was 83.3% in hydrocortisone group. Relapse of the disease one month after stopping treatment was not observed in both groups treated with sertaconazole 2 % cream and hydrocortisone 1% cream. Conclusion: Topical sertaconazole therapy is a considerable advance on treatment with corticosteroids. The cure rate was somewhat higher in the sertaconazole group and it can be considered as the nonsteroidal alternative to topical steroid therapy in seborrheic dermatitis.
Authors:
Mohamad Goldust; Mohamad Reza Ranjkesh; Mehdi Amirinia; Farideh Golforoushan; Elham Rezaee; Mohammad Amin Rezazadeh Saatlou
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-12-5
Journal Detail:
Title:  The Journal of dermatological treatment     Volume:  -     ISSN:  1471-1753     ISO Abbreviation:  J Dermatolog Treat     Publication Date:  2012 Dec 
Date Detail:
Created Date:  2012-12-5     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8918133     Medline TA:  J Dermatolog Treat     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Affiliation:
Medical student, Student research committee, Tabriz University of medical sciences , Tabriz , Iran.
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