Document Detail

Serratia marcescens outbreak in a neonatal intensive care unit related to the exit port of an oscillator.
MedLine Citation:
PMID:  21283042     Owner:  NLM     Status:  Publisher    
OBJECTIVE:: To interrupt transmission of Serratia marcescens colonization in a neonatal intensive care unit and determine the source of ongoing transmission. DESIGN:: Multidisciplinary outbreak investigation and simulation of droplet generation by a high-frequency oscillator using fluorescent dye. SETTING:: Level III neonatal intensive care unit. PATIENTS:: Very low birth weight premature infants with respiratory failure. INTERVENTIONS:: Infection control interventions, pulsed-field gel electrophoresis of isolates to determine relatedness, and construction of a scavenging system to capture the circuitry condensate expelled by the oscillator exit port. MEASUREMENTS AND MAIN RESULTS:: Affected infants were housed in the same geographic site. Serratia marcescens isolates were indistinguishable or closely related using pulsed-field gel electrophoresis. Fluorescent droplet splatter from the circuitry, generated when no containment device covered the exit valve, was visible up to 49 in (107.8 cm) from the source. CONCLUSIONS:: Implementation and adherence to infection control measures is essential to prevent transmission of opportunistic pathogens among ventilated infants. Oscillators can generate droplets that travel farther than 1 m from the source.
Tracy M Macdonald; Joanne M Langley; Tim Mailman; Kimberley Allain; George Nelson; Lydia Hatton; Timothy Sanford; Ken George; David Hancock; Dora Stinson; Michael R Mulvey
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2011-1-28
Journal Detail:
Title:  Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies     Volume:  -     ISSN:  1529-7535     ISO Abbreviation:  -     Publication Date:  2011 Jan 
Date Detail:
Created Date:  2011-2-1     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  100954653     Medline TA:  Pediatr Crit Care Med     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
From the Departments of Infection Prevention and Control Services (TMM, JML, KA), Pathology and Laboratory Medicine (JML, TM, GN), Respiratory Therapy (JML, LH, TS), and Biomedical Engineering (KG, DH), IWK Health Center, Halifax; Departments of Pediatrics (TM), Community Health and Epidemiology (DM), and Pathology, Dalhousie University, Halifax; and National Microbiology Laboratory (MRM), Public Health Agency of Canada, Ottawa, Canada.
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