Document Detail


Serotonin uptake and release by platelets adhering to polyethylene.
MedLine Citation:
PMID:  511018     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Heparinized human blood containing platelets labelled with 14C-serotonin and 51Cr was exposed to a polyethylene surface by rotation in Chandler loops. Both uptake of platelets on the surface and platelet aggregation in the blood occurred. More 14C- than 51Cr activity accumulated on the surface. It was demonstrated that this was due to an active uptake of 14C-serotonin by the surface-adherent platelets, which also retained their capacity to exert a release reaction.
Authors:
R Malmgren; R Larsson; P Olsson; K Rädegran
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Haemostasis     Volume:  8     ISSN:  0301-0147     ISO Abbreviation:  Haemostasis     Publication Date:  1979  
Date Detail:
Created Date:  1980-02-15     Completed Date:  1980-02-15     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0371574     Medline TA:  Haemostasis     Country:  SWITZERLAND    
Other Details:
Languages:  eng     Pagination:  400-8     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Blood Platelets / physiology*
Carbon Radioisotopes
Chromium Radioisotopes
Humans
Platelet Adhesiveness*
Polyethylenes*
Serotonin / metabolism*
Chemical
Reg. No./Substance:
0/Carbon Radioisotopes; 0/Chromium Radioisotopes; 0/Polyethylenes; 50-67-9/Serotonin

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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