| Serotonin immunoreactivity in the carotid body of adult humans. | |
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MedLine Citation:
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PMID: 8075479 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The distribution of serotonin immunoreactivity (-IR) was studied in adult human carotid bodies, obtained at post-mortem, using both the peroxidase-antiperoxidase method on paraffin sections and a double-labelling immunofluorescence on frozen sections. Antibodies against synaptophysin and protein gene product (PGP) 9.5 were used for identification of serotonin-IR cells. Serotonin-IR was demonstrable in the carotid bodies of adult humans and it was coexpressed mostly with synaptophysin or PGP 9.5 in type I cells. Some serotonin immunopositive type I cells were located in close proximity to capillaries. Serotonin-IR was also observed in a few endothelial cells. |
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Authors:
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J O Habeck; D J Pallot; W Kummer |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Histology and histopathology Volume: 9 ISSN: 0213-3911 ISO Abbreviation: Histol. Histopathol. Publication Date: 1994 Apr |
Date Detail:
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Created Date: 1994-10-05 Completed Date: 1994-10-05 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 8609357 Medline TA: Histol Histopathol Country: SPAIN |
Other Details:
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Languages: eng Pagination: 227-32 Citation Subset: IM |
Affiliation:
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Institute of Pathology, Muncipal Hospital, Chemnitz, Germany. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adolescent Aged Carotid Body / metabolism*, ultrastructure Female Fluorescent Antibody Technique Humans Immunohistochemistry Male Microscopy, Fluorescence Middle Aged Paraffin Embedding Serotonin / immunology, metabolism* Synaptophysin / immunology, metabolism Thiolester Hydrolases / immunology, metabolism Ubiquitin Thiolesterase |
| Chemical | |
Reg. No./Substance:
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0/Synaptophysin; 50-67-9/Serotonin; EC 3.1.2.-/Thiolester Hydrolases; EC 3.1.2.15/Ubiquitin Thiolesterase |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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