Document Detail

Serotonin-containing cell bodies in novel brain locations: effects of light input.
MedLine Citation:
PMID:  10203349     Owner:  NLM     Status:  MEDLINE    
Cell bodies staining positively for serotonin (5HT) appear in the suprachiasmatic nuclei (SCN) of hamsters that have been held in constant darkness (DD) for several months but are otherwise untreated. No such cell bodies are found in the SCN of animals that have been bilaterally enucleated for the same amount of time; however, in enucleated hamsters 5HT-containing cell bodies appear in the superior colliculus. These data provide the first indication that changes in sensory input can modulate 5HT levels in cells bodies outside of the raphe nuclei.
S Yamazaki; V Alones; W Irelan; M Menaker
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Publication Detail:
Type:  Journal Article; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  Neuroreport     Volume:  10     ISSN:  0959-4965     ISO Abbreviation:  Neuroreport     Publication Date:  1999 Feb 
Date Detail:
Created Date:  1999-06-03     Completed Date:  1999-06-03     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  9100935     Medline TA:  Neuroreport     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  431-5     Citation Subset:  IM    
Department of Biology and NSF Center for Biological Timing, University of Virginia, Charlottesville 22903, USA.
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MeSH Terms
Brain / cytology,  metabolism*
Eye Enucleation
Immunohistochemistry / methods
Neurons / metabolism*
Raphe Nuclei / cytology,  metabolism
Serotonin / metabolism*
Staining and Labeling
Superior Colliculi / cytology,  metabolism
Suprachiasmatic Nucleus / cytology,  metabolism
Tissue Distribution / physiology
Grant Support
Reg. No./Substance:
Erratum In:
Neuroreport 1999 Apr 26;10(6):inside back cov

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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