Document Detail

Serotonin and catecholaminergic polymorphic ventricular tachycardia: a possible therapeutic role for SSRIs?
MedLine Citation:
PMID:  20838725     Owner:  NLM     Status:  MEDLINE    
Catecholaminergic polymorphic ventricular tachycardia (CPVT) is a rare malignant arrhythmia, usually diagnosed in the adolescent years. The diagnosis can typically be made by one or more of the following: a positive family history, exercise electrocardiography, ambulatory ECG monitoring and/or an intra-cardiac, electrophysiological examination. This is a case report of a patient with CPVT that was refractory to treatment with beta-blockade and an implanted automatic cardioverter defibrillator. However, after a selective serotonin re-uptake inhibitor (SSRI) was added to the therapeutic regimen, no further episodes of ventricular tachycardia occurred during the following two years.
S Chen; Q Duan; K Tang; D Zhao; Y Xu
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Cardiovascular journal of Africa     Volume:  21     ISSN:  1995-1892     ISO Abbreviation:  Cardiovasc J Afr     Publication Date:    2010 Jul-Aug
Date Detail:
Created Date:  2010-09-14     Completed Date:  2010-10-20     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101313864     Medline TA:  Cardiovasc J Afr     Country:  South Africa    
Other Details:
Languages:  eng     Pagination:  225-8     Citation Subset:  IM    
Department of Cardiology, 10th People's Hospital of Tongji University, Shanghai, China.
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MeSH Terms
Catecholamines / metabolism
Paroxetine / therapeutic use*
Serotonin Uptake Inhibitors / therapeutic use*
Tachycardia, Ventricular / diagnosis,  drug therapy*
Young Adult
Reg. No./Substance:
0/Catecholamines; 0/Serotonin Uptake Inhibitors; 61869-08-7/Paroxetine

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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