Document Detail

Serotonin antagonism in panic disorder: an open trial with ritanserin.
MedLine Citation:
PMID:  3152708     Owner:  NLM     Status:  MEDLINE    
Eleven patients with panic disorder were administered ritanserin, a post-synaptic serotonin S2 antagonist, during a 4 week period at a daily dose of 10-20 mg. The treatment resulted in a decrease in the number of panic attacks, and a diminution of agoraphobic avoidance. The possible practical and theoretical signification of these findings is discussed.
E Griez; H Pols; H Lousberg
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Acta psychiatrica Belgica     Volume:  88     ISSN:  0300-8967     ISO Abbreviation:  Acta Psychiatr Belg     Publication Date:  1988  
Date Detail:
Created Date:  1990-08-30     Completed Date:  1990-08-30     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0247037     Medline TA:  Acta Psychiatr Belg     Country:  BELGIUM    
Other Details:
Languages:  eng     Pagination:  372-7     Citation Subset:  IM    
State University of Limburg, Department of Clinical Psychiatry, Maastricht, The Netherland.
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MeSH Terms
Agoraphobia / drug therapy
Escape Reaction / drug effects
Fear / drug effects*
Panic / drug effects*
Phobic Disorders / drug therapy*
Piperidines / therapeutic use*
Serotonin Antagonists / therapeutic use*
Reg. No./Substance:
0/Piperidines; 0/Serotonin Antagonists; 87051-43-2/Ritanserin

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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