Document Detail


Serotonergic neurons of the Drosophila air-puff-stimulated flight circuit.
MedLine Citation:
PMID:  25116612     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
Monoaminergic modulation of insect flight is well documented. Recently, we demonstrated that synaptic activity is required in serotonergic neurons for Drosophila flight. This requirement is during early pupal development, when the flight circuit is formed, as well as in adults. Using a Ca2+-activity-based GFP reporter, here we show that serotonergic neurons in both prothoracic and mesothoracic segments are activated upon air-puff-stimulated flight. Moreover ectopic activation of the entire serotonergic system by TrpA1, a heat activated cation channel, induces flight, even in the absence of an air-puff stimulus.
Authors:
Sufia Sadaf; Gaiti Hasan
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of biosciences     Volume:  39     ISSN:  0973-7138     ISO Abbreviation:  J. Biosci.     Publication Date:  2014 Sep 
Date Detail:
Created Date:  2014-08-13     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8100809     Medline TA:  J Biosci     Country:  India    
Other Details:
Languages:  eng     Pagination:  575-83     Citation Subset:  IM    
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