| Serotonergic modulation of ingestive behavior in pigeons. | |
| | |
MedLine Citation:
|
PMID: 2524843 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
The effects of peripheral administration of the serotonin agonist zimeldine and the serotonin antagonist cyproheptadine on food and water consumption were evaluated in domestic pigeons. Injections of zimeldine reduced the amount of feeding and drinking dose-dependently in 24-hr fasted animals. Administration of cyproheptadine enhanced food and water consumption dose-dependently up to a dose of 160 micrograms per 100 g body weight in nondeprived pigeons. Higher doses reduced ingestion probably due to a general behavioral depression. The effect of zimeldine was antagonized by cyproheptadine. It is concluded that, as in mammals, serotonin participates as an inhibitor in the regulation of feeding in birds. Contrary to the situation in mammals it has no activating effect on drinking but leads to a reduction of water consumption in pigeons. |
| | |
Authors:
|
O Güntürkün; A Grothues; A Hautkappe; F Visé; N Wawrzyniak; U Zwilling |
Related Documents
:
|
16822973 - Food-induced behavioral sensitization, its cross-sensitization to cocaine and morphine,... 2998563 - Effects of kappa opiate agonists on palatable food consumption in non-deprived rats, wi... 16373943 - Reproducibility and validity of a food frequency questionnaire among vietnamese in ho c... |
Publication Detail:
|
Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
|
Title: Pharmacology, biochemistry, and behavior Volume: 32 ISSN: 0091-3057 ISO Abbreviation: Pharmacol. Biochem. Behav. Publication Date: 1989 Feb |
Date Detail:
|
Created Date: 1989-07-12 Completed Date: 1989-07-12 Revised Date: 2006-11-15 |
Medline Journal Info:
|
Nlm Unique ID: 0367050 Medline TA: Pharmacol Biochem Behav Country: UNITED STATES |
Other Details:
|
Languages: eng Pagination: 415-20 Citation Subset: IM |
Affiliation:
|
FB Psychologie, Universität Konstanz, FRG. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Animals Columbidae Cyproheptadine / pharmacology Drinking Behavior / physiology* Drug Interactions Feeding Behavior / physiology* Female Male Pimozide / pharmacology Serotonin / physiology* Time Factors Zimeldine / pharmacology |
| Chemical | |
Reg. No./Substance:
|
129-03-3/Cyproheptadine; 2062-78-4/Pimozide; 50-67-9/Serotonin; 56775-88-3/Zimeldine |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Molecular cloning of cDNA encoding Sm autoantigen: derivation of a cDNA for a B polypeptide of the U...
Next Document: Dextrofenfluramine, but not 8-OH-DPAT affects the decrease in food consumed by rats submitted to phy...