| Serotonergic agents in the treatment of fibromyalgia syndrome. | |
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MedLine Citation:
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PMID: 11918524 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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OBJECTIVE: To evaluate literature that discusses the treatment of fibromyalgia syndrome (FMS) with agents that involve the neurotransmitter serotonin. DATA SOURCES: Biomedical literature accessed through MEDLINE (1966-August 2001) and International Pharmaceutical Abstracts. DATA SYNTHESIS: The cause and pathophysiology of FMS remain elusive, although abnormalities in the serotonin pathway have been implicated. Several serotonergic agents have been studied for use in FMS. Trials and case reports focusing on the use of newer agents: the selective serotonin reuptake inhibitors, venlafaxine and tramadol, were reviewed. CONCLUSIONS: Current research suggests that the serotonergic agents may reduce at least some of the symptoms of FMS. However, medications that act on multiple neurotransmitters may prove to be more effective in symptom management. Additional long-term studies are required in order to validate these results. |
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Authors:
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Lisa J Miller; Kristy L Kubes |
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Publication Detail:
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Type: Journal Article; Review |
Journal Detail:
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Title: The Annals of pharmacotherapy Volume: 36 ISSN: 1060-0280 ISO Abbreviation: Ann Pharmacother Publication Date: 2002 Apr |
Date Detail:
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Created Date: 2002-03-28 Completed Date: 2002-07-24 Revised Date: 2007-11-15 |
Medline Journal Info:
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Nlm Unique ID: 9203131 Medline TA: Ann Pharmacother Country: United States |
Other Details:
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Languages: eng Pagination: 707-12 Citation Subset: IM |
Affiliation:
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Pharmacy Department, Memorial Hermann Southwest Hospital, Houston, TX 77074, USA. lisa_miller@mhhs.org |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Clinical Trials as Topic Female Fibromyalgia / drug therapy*, metabolism Humans MEDLINE Male Serotonin / metabolism Serotonin Uptake Inhibitors / therapeutic use* Treatment Outcome |
| Chemical | |
Reg. No./Substance:
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0/Serotonin Uptake Inhibitors; 50-67-9/Serotonin |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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