Document Detail

Seroprevalence of measles-specific antibodies in the group predominantly affected by measles in 2006-2009 in Poland.
MedLine Citation:
PMID:  25391004     Owner:  NLM     Status:  Publisher    
INRODUCTION: Irrespective of the high vaccination coverage against measles, sporadic measles outbreaks still occur in Poland. In 2006-2009, a slight increase in the number of measles cases was observed. Of these cases, people born in 1976-198 9 were predominantly affected.
AIM: The aim of the study was to evaluate the immunity to measles in the aforesaid age group.
MATERIALAND METHODS: The serum samples were selected from the serum bank in which material collected from the general population living in 5 provinces in Poland is stored. These samples were collected from patients hospitalized due to emergencies in 2010-2011. The antibody titre against measles was determined in each serum sample by ELISA test (Genzyme Virotech). Linear regression models using log-transformed antibody titres were used to compare the values.
RESULTS: The serum samples collected from 483 persons, including 111 females and 372 males were tested. All patients had antibody titres exceeding 0.5 IU/ml. The antibody titre was statistically significantly associated with the vaccination coverage in each age group in particular province.
CONCUSIONS: The results of this study suggest good immunity to measles in the general population in Poland. The disparities between randomly selected provinces demonstrated a relation with the coverage rates as well as the differences in measles incidence which is observed recently between these provinces.
KEY WORDS: measles, antibody titre, Polish population.
Agata Makówka; Magdalena Rosińska; Włodzimierz Gut; Bogumiła Litwińska
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Publication Detail:
Journal Detail:
Title:  Przeglad epidemiologiczny     Volume:  68     ISSN:  0033-2100     ISO Abbreviation:  Przegl Epidemiol     Publication Date:  2014  
Date Detail:
Created Date:  2014-11-12     Completed Date:  -     Revised Date:  2014-11-13    
Medline Journal Info:
Nlm Unique ID:  0413725     Medline TA:  Przegl Epidemiol     Country:  -    
Other Details:
Languages:  ENG; POL     Pagination:  411-416     Citation Subset:  -    
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