Document Detail

Seroprevalence and incidence of Toxoplasma gondii infection in the Legnano area of Italy.
MedLine Citation:
PMID:  18034857     Owner:  NLM     Status:  MEDLINE    
The decreasing prevalence of anti-Toxoplasma antibodies in Europe has re-opened the question of the appropriateness of serological screening during pregnancy. A study of 3426 pregnant women, resident in the Legnano area of Italy, revealed that the IgG seroprevalence according to ELISA was 21.5%, and that of IgM according to ELISA and enzyme-linked fluorescent assay was 1.2% and 0.9%, respectively. The incidence of infection, estimated on the basis of IgG avidity, was 0.9%. These results confirm a decrease in the prevalence of IgG, but indicate a high incidence of infection, thus suggesting that screening for anti-Toxoplasma antibodies during pregnancy should be maintained.
M De Paschale; C Agrappi; P Clerici; P Mirri; M T Manco; S Cavallari; E F Viganò
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Publication Detail:
Type:  Journal Article     Date:  2007-11-22
Journal Detail:
Title:  Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases     Volume:  14     ISSN:  1198-743X     ISO Abbreviation:  Clin. Microbiol. Infect.     Publication Date:  2008 Feb 
Date Detail:
Created Date:  2008-01-10     Completed Date:  2008-09-23     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9516420     Medline TA:  Clin Microbiol Infect     Country:  France    
Other Details:
Languages:  eng     Pagination:  186-9     Citation Subset:  IM    
Microbiology Unit, Hospital of Legnano, Legnano (Milan), Italy.
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MeSH Terms
Antibodies, Protozoan / blood*
Antibody Affinity
Enzyme-Linked Immunosorbent Assay
Immunoglobulin G / blood
Immunoglobulin M / blood
Italy / epidemiology
Models, Biological
Pregnancy Complications, Parasitic / epidemiology*
Seroepidemiologic Studies
Toxoplasma / immunology*
Toxoplasmosis / epidemiology*
Reg. No./Substance:
0/Antibodies, Protozoan; 0/Immunoglobulin G; 0/Immunoglobulin M

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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