| Seroprevalence of antibodies to microorganisms known to cause arterial and myocardial damage in patients with or without coronary stenosis. | |
| | |
MedLine Citation:
|
PMID: 11527817 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
Infections are assumed to play a role in coronary artery disease (CAD) and cardiomyopathies. It is unknown whether the seroprevalence of antibodies to these microorganisms is higher in patients with than without CAD. The seroprevalence of antibodies to Bartonella henselae, Borrelia burgdorferi, Chlamydia pneumoniae, Coxiella burnetii, Helicobacter pylori, human granulocytic Ehrlichia, Leptospira, Rickettsia conorii, and Treponema pallidum was assessed prospectively in patients with exertional dyspnea or anginal chest pain who underwent coronary angiography because of suspected CAD. Patients with normal angiograms (NA) were those in whom no more than 50% stenosis of any coronary artery was found. Patients with CAD were patients who underwent percutaneous transluminal coronary angioplasty. There were 50 patients with CAD (9 female) and 62 with NA (25 female), with a mean age of 62 years. All patients had antibodies to at least one microorganism: to B. henselae, 8% of CAD patients and 5% of NA patients; to B. burgdorferi IgG, 14% CAD and 6% NA; to B. burgdorferi IgM, 6% CAD and 3% NA; to C. pneumoniae lipopolysaccharide (LPS) IgA, 76% CAD and 77% NA; to C. pneumoniae LPS IgG, 80% CAD and 90% NA; to C. burnetii, 0% CAD and 5% NA; to H. pylori, 92% CAD and 68% NA; to human granulocytic Ehrlichia, 8% CAD and 3% NA; to Leptospira IgG, 4% CAD and 2% NA; to R. conorii, 10% in both groups; and to T. pallidum, 2% CAD and 0% NA. The seroprevalence of antibodies to micro-organisms known to induce arterial and myocardial damage does not differ between patients with CAD and NA. |
| | |
Authors:
|
C Stöllberger; G Mölzer; J Finsterer |
Related Documents
:
|
19153177 - Prognostic utility of 64-slice computed tomography in patients with suspected but no do... 20460497 - Incremental prognostic value of coronary ct angiography in patients with suspected coro... 16485057 - Noninvasive assessment of coronary artery disease in diabetic patients: the role of str... 12867307 - Success changes the problem: why ventricular fibrillation is declining, why pulseless e... 6696547 - Effects of oral amiodarone on left ventricular function in dogs: clinical implications ... 12140807 - The potential of brain natriuretic peptide as a biomarker for new york heart associatio... |
Publication Detail:
|
Type: Journal Article |
Journal Detail:
|
Title: Clinical and diagnostic laboratory immunology Volume: 8 ISSN: 1071-412X ISO Abbreviation: Clin. Diagn. Lab. Immunol. Publication Date: 2001 Sep |
Date Detail:
|
Created Date: 2001-08-30 Completed Date: 2001-12-04 Revised Date: 2013-04-17 |
Medline Journal Info:
|
Nlm Unique ID: 9421292 Medline TA: Clin Diagn Lab Immunol Country: United States |
Other Details:
|
Languages: eng Pagination: 997-1002 Citation Subset: IM |
Affiliation:
|
Medizinische Abteilung der Krankenanstalt Rudolfstiftung, Steingasse 31/18, A-1030 Vienna, Austria. claudia.stoellberger@chello.at |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Adult Aged Antibodies, Bacterial / blood* Bartonella / immunology Coronary Artery Disease / epidemiology, immunology, microbiology* Coronary Stenosis / epidemiology, immunology, microbiology* Female Gram-Negative Bacteria / immunology*, pathogenicity Gram-Negative Bacterial Infections / epidemiology, immunology Humans Male Middle Aged Myocarditis / epidemiology, immunology, microbiology* Prospective Studies Seroepidemiologic Studies |
| Chemical | |
Reg. No./Substance:
|
0/Antibodies, Bacterial |
| Comments/Corrections | |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Anti-CD20 monoclonal antibody treatment of human herpesvirus 8-associated, body cavity-based lymphom...
Next Document: Effects of calorie restriction on polymicrobial peritonitis induced by cecum ligation and puncture i...