Document Detail


Seroprevalence of Chlamydia trachomatis in Enugu, Nigeria.
MedLine Citation:
PMID:  21860135     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
Background: Chlamydia infections in women cause pelvic inflammatory disease, which often results in devastating consequences of infertility, ectopic pregnancy, or chronic pelvic pain. The infection is largely asymptomatic. Objective: To determine the seroprevalence of Chlamydia trachomatis in Enugu, South Eastern Nigeria. Materials and Methods: A population-based prospective study comprising female residents of Enugu, South Eastern Nigeria. Indirect solid phase enzyme immunoassay of Chlamydia antibodies was done using ImmunoComb C0. Trachomatis IgG Kit (Orgenics). Results: The population comprised 136 female undergraduate students and 150 non-student women. The overall prevalence of C. trachomatis in the population studied was 29.4%. The percentage of subjects who admitted to be having multiple sexual partners was higher among the student population (71.2%) compared to those from the non-student population (28.8%). The highest percentage of seroprevalence was 28 (33.3%) in the age group of 20-24 years for the student population and 18 (21.4%) in the age group of 25-29 years for the non-student population. The highest seroprevalence of C. trachomatis antibodies (69.0%) in both populations was observed in females without any history of infection. Females that had pelvic inflammatory disease, sexually transmitted infection, and secondary infertility assayed for C. trachomatis had seroprevalence levels of 19%, 9.5%, and 2.4%, respectively. There was a positive correlation between positive Chlamydia assay and the type of subject population (student or non-student) with r2 value of 1.55 at P < 0.01. Conclusions: C. trachomatis infection is largely underdiagnosed and remains a silent disease in the apparently healthy population of Enugu, South eastern Nigeria.
Authors:
A C Ikeme; H U Ezegwui; L C Ikeako; I Agbata; E Agbata
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Nigerian journal of clinical practice     Volume:  14     ISSN:  1119-3077     ISO Abbreviation:  Niger J Clin Pract     Publication Date:    2011 Apr-Jun
Date Detail:
Created Date:  2011-08-23     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101150032     Medline TA:  Niger J Clin Pract     Country:  India    
Other Details:
Languages:  eng     Pagination:  176-80     Citation Subset:  IM    
Affiliation:
Department of Obstetrics and Gynaecology,Anambra State-University Teaching Hospital, Amaku, Awka, Nigeria.
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