Document Detail

Serologically Determined in Utero Exposure to Oral Pathogens may be Associated with Increased Risk for Neonatal Intensive Care Unit (NICU) Admissions and Length of Stay.
MedLine Citation:
PMID:  23253829     Owner:  NLM     Status:  In-Data-Review    
KEY EXPOSURE/STUDY FACTOR: Fetal immunoglobulin M (IgM) antibody to periodontal organisms.
MAIN OUTCOME MEASURE: Infant admission to the neonatal intensive care unit (NICU) and total length of NICU hospitalization.
MAIN RESULTS: The primary results were that infants with serological evidence of exposure (as measured by IgM antibody) to periodontal organisms had a higher rate of NICU admission when compared with seronegative infants (11% versus 5% respectively), adjusting for gestational age, and seropositive infants were more likely than seronegative infants to stay more than 3 or more than 7 days at the NICU. Similarly, NICU patterns were not detected for infant umbilical cord serum C-reactive protein (CRP) levels.
CONCLUSIONS: The authors concluded that in utero fetal exposure to oral pathogens increases the risk for NICU admissions and length of stay.
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The journal of evidence-based dental practice     Volume:  12     ISSN:  1532-3390     ISO Abbreviation:  J Evid Based Dent Pract     Publication Date:  2012 Sep 
Date Detail:
Created Date:  2012-12-20     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101083101     Medline TA:  J Evid Based Dent Pract     Country:  United States    
Other Details:
Languages:  eng     Pagination:  34-5     Citation Subset:  D; IM    
Copyright Information:
Copyright © 2012. Published by Mosby, Inc. All rights reserved.
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