Document Detail

Serological screening tests for syphilis in pregnancy: results of a five year study (1983-87) in the Oxford region.
MedLine Citation:
PMID:  2515214     Owner:  NLM     Status:  MEDLINE    
Between 1983 and 1987, 62 out of 76519 pregnancies in 51 mothers had a positive miniaturised Treponema pallidum haemagglutination assay (TPHA) test--1 in 1234, or 0.81 per 1000 births. About two thirds of these mothers had syphilis and the remainder non-venereal treponematoses such as yaws or pinta. Antenatal screening identified 13 patients with previously unknown acquired syphilis, 11 of whom were given antibiotics during pregnancy. There were six fetal losses among the 62 TPHA positive pregnancies, but none had evidence of congenital syphilis. No live born child in this study group showed stigmata of congenital syphilis. It is concluded that despite the current low incidence of syphilis in the United Kingdom it is imperative to continue antenatal serological screening and to emphasise the importance of early adequate treatment of the infection.
P Bowell; K Mayne; A Puckett; C Entwistle; J Selkon
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of clinical pathology     Volume:  42     ISSN:  0021-9746     ISO Abbreviation:  J. Clin. Pathol.     Publication Date:  1989 Dec 
Date Detail:
Created Date:  1990-03-09     Completed Date:  1990-03-09     Revised Date:  2009-11-18    
Medline Journal Info:
Nlm Unique ID:  0376601     Medline TA:  J Clin Pathol     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  1281-4     Citation Subset:  AIM; IM    
Regional Blood Transfusion Centre, John Radcliffe Hospital, Oxford.
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MeSH Terms
Cost-Benefit Analysis
Hemagglutination Tests
Infant, Newborn
Mass Screening*
Pinta / diagnosis
Pregnancy Complications, Infectious / prevention & control*
Prenatal Diagnosis
Retrospective Studies
Syphilis / epidemiology
Syphilis Serodiagnosis*
Syphilis, Congenital / prevention & control
Yaws / diagnosis

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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